DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and Lipo1

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_006231364.1	Gene:	Lipo1 / 294097	RGDID:	1565682	Length:	397	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	125/394 - (31%)
Similarity:	199/394 - (50%)	Gaps:	52/394 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 AERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFL 100
            :|.|....||:..:.|.|.|||:|.:.||||. |.|:|     |.|.:.||...|||||....::
  Rat    34 SEIIKYWNYPSLEYEVVTDDGYILPINRIPHG-KNNAN-----SSAPKMVVFCQHGLFSTPGVWV 92

  Fly   101 LNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILA 165
            .|.|:::|.:..|:|||||||||:||:.:::.:..|:.....||.||:.::.:.||||||::||.
  Rat    93 ANPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEEFWAFSFDQMIAYDLPATINFILN 157

  Fly   166 ETGQQSLHYVGHSQGCTSFFVMGSY--RPEYNAKIKTAHMLAPPVYMGNSTEG---LIVSTAP-- 223
            .|||:.::|:|||.|  :...:|::  ..|...||| .::|..||......:|   |:...:|
  Rat   158 TTGQEQIYYIGHSLG--TLIALGAFSTNQELAEKIK-LNILIAPVRTVKYVKGFGRLLAYFSPEA 219

  Fly   224 ---LFGHHGIGSTLLENQVLLPQNAFIQ--------RVLDTTCSNQPIMLSYCKTLAILWGGPEI 277
               :||          .:..||...|.:        :::|..|:.         .|..|.|..|
  Rat   220 FKLVFG----------KKEFLPTVVFSEYSKYVCNIKLVDAGCAG---------VLGSLTGFSE- 264

  Fly   278 GNLNQTLLPQIAETHP-AGVSSNQAIHYIQSYASNDFRLYDWGS-KRNLEYYGVSEPPAYDLTKI 340
            ..||.:.: .:..||. ||.|:...||..|:..|.:|:.||||| ..|:::|..:.||.|.:..:
  Rat   265 DQLNTSRI-DVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENM 328

  Fly   341 TSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSK 405
            .....::.||.|..|:.:|::.|...:.||.....:|:  :.|||||.....|..::|.:|....
  Rat   329 KVPTVMFTGLKDFLADPKDVANLVPKIFNLIYHKTIPE--FSHLDFIVGLNAKTEVSDEILTILG 391

  Fly   406 AYDA 409
            .||:
  Rat   392 EYDS 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	120/376 (32%)
		Abhydro_lipase	36..103	CDD:282003	26/66 (39%)
		Abhydrolase	113..>196	CDD:304388	35/84 (42%)
Lipo1	XP_006231364.1	Abhydro_lipase	33..94	CDD:282003	26/65 (40%)
		Abhydrolase_1	77..375	CDD:278959	101/323 (31%)
		Abhydrolase_5	77..>199	CDD:289465	49/124 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335471
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.810