DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	377	Identity:	113/377 - (29%)
Similarity:	170/377 - (45%)	Gaps:	43/377 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 AEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASR--PVVLIMHGLFSCSDCFLLN 102
            |.|||..|.|||.|.|||:|.:.|:....|       |:.|...  |.||.:|||...|:.::.|
pombe    80 ALHGYDLEEHFVRTTDGYLLGLHRVYKKKK-------GKIEELNYLPPVLFIHGLMMNSESWVCN 137

  Fly   103 -GPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAE 166
             ..|||:|:...:.||||||||.|||.||..|.:.:.::|.||.||...|...|:|:.:.|||:.
pombe   138 LKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIPSIVKYILSV 202

  Fly   167 TGQQSLHYVGHSQGCTSFFVMGS----YRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPL--- 224
            ....|:..||.|||....|...|    .|....|.|..|..:||..|.|.:.:.:|.:.:.|
pombe   203 NSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSIIHANSQLLYL 267

  Fly   225 -FGHHG-IGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQ 287
             ||.:. :||.:....||.|  ....:::|       :.|.:    .:.|.|..|....:.
pombe   268 MFGRNSMLGSAVFWQAVLYP--PVFAKIVD-------LFLRF----FLSWTGKNISETQKI---- 315

  Fly   288 IAETHPAGVSSNQA-IHYIQSYASNDFRLYDWGSKRNLEYY-GVSEPPAYDLTKITSELYLYYGL 350
            :|.:|....:|.:. :|:.|.......::||........|| .::....|.:..|...:.|.||.
pombe   316 VAYSHLYSFTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYTNLNRIARYPIENIRLPITLVYGS 380

  Fly   351 ADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLD 402
            .|   |..||..|...||.|:...::|:  :.|||.|.....|.::...|::
pombe   381 ND---NMVDIETLKTQLPPLSQCIQIPN--YEHLDIIMGDTKKDIVIQQVVE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	111/366 (30%)
		Abhydro_lipase	36..103	CDD:282003	25/65 (38%)
		Abhydrolase	113..>196	CDD:304388	34/86 (40%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	24/64 (38%)
		Abhydrolase_1	119..412	CDD:278959	93/314 (30%)
		Abhydrolase_5	120..>260	CDD:289465	53/139 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	10	9.770