DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and Lipa

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_036864.3	Gene:	Lipa / 25055	RGDID:	3008	Length:	397	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	143/411 - (34%)
Similarity:	212/411 - (51%)	Gaps:	34/411 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLAKVLT-ILAIVASAGAADDF---DPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNV 61
            :|.:|:. ::.|:.|.|.....   ||..::      ...|.|...|||.|.|.|:|.|||:|.|
  Rat     3 LLGRVICFVVGILLSGGPTGTISAVDPEANM------NVTEIIMHWGYPGEEHSVQTGDGYILGV 61

  Fly    62 FRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARG 126
            .||||..|     |:.: :..:|||.:.||..:.|..::.|...::|.:..||||:|||:||:||
  Rat    62 HRIPHGRK-----NQFD-KGPKPVVYLQHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRG 120

  Fly   127 NIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYR 191
            |.:||.:..|:|....:|.||:.|:...||||:|:|||.:|||:.|:|||||||||..|:..|..
  Rat   121 NTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKTGQEQLYYVGHSQGCTIGFIAFSQM 185

  Fly   192 PEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGSTLLEN----QVLLPQNAFIQRVLD 252
            ||...|:|....|||.:.: |...|.:|....|      ...|||:    :..|||:|.: :.|.
  Rat   186 PELAKKVKMFFALAPVLSL-NFASGPMVKLGRL------PDLLLEDLFGQKQFLPQSAMV-KWLS 242

  Fly   253 TTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETH-PAGVSSNQAIHYIQSYASNDFRLY 316
            |......||...|..:..|..|....|||.:.: .:..|| |||.|....:|:.|....:..:.:
  Rat   243 THICTHVIMKELCANIFFLICGFNEKNLNMSRV-DVYTTHCPAGTSVQNMVHWTQVVKYHKLQAF 306

  Fly   317 DWGSK-RNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDST 380
            ||||. :|..:|..|.||.|.:..:.....|:.|..|..|:..||:.|...:|.|.....:|:
  Rat   307 DWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHKNIPE-- 369

  Fly   381 WGHLDFIFATEVK-RVINDLV 400
            |.|||||:..:.. |:.|::|
  Rat   370 WDHLDFIWGLDAPWRLYNEVV 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	139/397 (35%)
		Abhydro_lipase	36..103	CDD:282003	26/66 (39%)
		Abhydrolase	113..>196	CDD:304388	45/82 (55%)
Lipa	NP_036864.3	PLN02872	7..394	CDD:215470	142/407 (35%)
		Abhydro_lipase	35..96	CDD:282003	26/66 (39%)
		Abhydrolase_5	78..>203	CDD:289465	58/124 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335496
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.810