DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and Lipo2

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001309267.1	Gene:	Lipo2 / 101055671	MGIID:	3644466	Length:	398	Species:	Mus musculus

Alignment Length:	380	Identity:	117/380 - (30%)
Similarity:	193/380 - (50%)	Gaps:	26/380 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 AERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFL 100
            :|.|....||:|.:.|.|.|||:|.:.||||..      |..:|.|.:.||...|||.:....::
Mouse    34 SEIIKHWDYPSEEYEVVTDDGYILPINRIPHGK------NNAKSPAPKMVVFCQHGLLATPGAWV 92

  Fly   101 LNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILA 165
            .|.|.::|.:..||||||||:|::||:.:::.:..||.....||.||:.::...||||||::||.
Mouse    93 SNPPVNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNPDSKEFWDFSFDQMIKYDLPATINFILD 157

  Fly   166 ETGQQSLHYVGHSQGCTSFFVMGSY--RPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHH 228
            :|||:.::|:|||||  :...:|::  ..:...|||...:|| |:|....::|:        .|.
Mouse   158 KTGQKQIYYIGHSQG--TLLAIGAFATNQKLAEKIKLNILLA-PIYSVQHSKGI--------SHL 211

  Fly   229 GIGSTLLENQVLLPQNAFIQRVLDT---TC-SNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIA 289
            ....|....::|..:..|:..|:.:   .| .|.....:.|..:....||.....||::.|....
Mouse   212 ASYLTPTTIKLLFGEKEFLPTVVFSEVGACVCNINFFTAICAAIMGSMGGYSPEELNKSRLDVYV 276

  Fly   290 ETHPAGVSSNQAIHYIQSYASNDFRLYDWGS-KRNLEYYGVSEPPAYDLTKITSELYLYYGLADG 353
            :.:.||.|....|||.|...|...:.||||| ..|:.:|..:.||.|::..:.....::.||.|.
Mouse   277 KLNLAGTSVKVLIHYNQVGRSGILQAYDWGSPSLNMRHYNQTTPPVYNVEDMKVPTAMFTGLKDF 341

  Fly   354 SANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYD 408
            .::.:|:..|...:.||..|..:||  :.|.|||:....:..:::.:|...:.||
Mouse   342 LSDPEDVEILKPKIHNLTYLKTIPD--FSHFDFIWGLNTREEVSEEILTILRKYD 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	114/363 (31%)
		Abhydro_lipase	36..103	CDD:282003	23/66 (35%)
		Abhydrolase	113..>196	CDD:304388	35/84 (42%)
Lipo2	NP_001309267.1	PLN02872	34..391	CDD:215470	115/375 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760