DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and LOC100360690

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_006231366.1	Gene:	LOC100360690 / 100360690	RGDID:	2321667	Length:	399	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	125/374 - (33%)
Similarity:	191/374 - (51%)	Gaps:	19/374 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNG 103
            |:..||.:|.|.|.|.|||:|.:|||||    ..|.|:......||||.:.|||...:|.::|:.
  Rat    38 ISYWGYESEEHEVMTEDGYILLIFRIPH----GKNENKSSHNTRRPVVYLHHGLTVSADYWILDP 98

  Fly   104 PEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETG 168
            |.:.|.:..||||::|||||:||...:|.:.||:.....||.||::|....||||.|.:||.||.
  Rat    99 PSNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDSKEFWDFSFNEQIEYDLPAIIYFILNETR 163

  Fly   169 QQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGST 233
            |..::|:|||||....:...:..|:...|||....|.|.|.....| |:..:.|  :.|..:..|
  Rat   164 QTQIYYIGHSQGVYLAYAAFATNPQLAQKIKINFALGPVVITKYLT-GVFRTIA--YIHPTVIKT 225

  Fly   234 LL-ENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETHPAGVS 297
            :. |..:....||  ..:|...|..:.|..: |.:|.|:..|...||||::.:...:|..|||.|
  Rat   226 MFGEKDIFSKSNA--NDILRFLCHREQIATA-CTSLLIVLFGYNPGNLNESRIDVYSEHIPAGTS 287

  Fly   298 SNQAIHYIQSYASNDFRLYDWGSKR-NLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDIS 361
            ....:|:.|...|..|:.|||||:. |:.:|..|.||.|::..:.....::.|..|...:.:|:.
  Rat   288 VRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPIYNIEDMKVRTAMWSGERDLLGDPKDVK 352

  Fly   362 RLPDLLPNLALLHEVPDSTWGHLDFIFATEV-----KRVINDLVLDYSK 405
            .|....|||....::|.  :.|:|||...:.     :::|..:..|.|:
  Rat   353 NLAAKTPNLIYHKKIPH--YNHMDFILGKDAVVQVYRKIIEFINRDQSE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	122/360 (34%)
		Abhydro_lipase	36..103	CDD:282003	27/63 (43%)
		Abhydrolase	113..>196	CDD:304388	36/82 (44%)
LOC100360690	XP_006231366.1	Abhydro_lipase	34..96	CDD:282003	26/61 (43%)
		Abhydrolase_1	79..378	CDD:278959	103/306 (34%)
		Abhydrolase_5	79..245	CDD:289465	61/170 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335472
Domainoid	1	1.000	64	1.000	Domainoid score	I9870
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910