Protein Alignment Pgant2 and GALNT14

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001240755.1
• Gene: GALNT14 / 79623
• HGNCID: 22946
• Length: 557
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 244/449 - (54%)
• Similarity: 321/449 - (71%)
• Gaps: 15/449 - (3%)

  Fly   192 CRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKI 256
            |....|..|||.||:||||||||||||||||.|||||:|.||||||:||||:|:.|:|..:|.|:
Human   106 CTLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSNDPDDCKQLIKL 170

  Fly   257 DKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDV 321
            .||:.:||::|:||||||::|||.|..:.|||||||.|.|..||:|||.||:||.|||||||||:
Human   171 PKVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDI 235

  Fly   322 ISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNK 386
            |::|.|.||.::::|||||||:|.|:||.|||.::| |..|||..||||:|||||||||||:|:.
Human   236 INLDTFTYIESASELRGGFDWSLHFQWEQLSPEQKA-RRLDPTEPIRTPIIAGGLFVIDKAWFDY 299

  Fly   387 LGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAA 451
            ||||||.||:|||||.|||||||.|||||||:|||||||||||:|||.||.|:.|.:.:||:|.|
Human   300 LGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTA 364

  Fly   452 EVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDPQEV--GQF 514
            |||||:|||:||.|.|.|...||||::.||.|::.|.|:.|||||||:||:|..|....:  |..
Human   365 EVWMDEYKQYYYAARPFALERPFGNVESRLDLRKNLRCQSFKWYLENIYPELSIPKESSIQKGNI 429

  Fly   515 RQDSTECLDTMGHLIDGT--VGIFPCHNTGG----NQEWAFTKRGEIKHDDLCLTLVTFARGSQV 573
            || ..:||::.......|  :.:.||....|    :|.||||...:|..::|||:::|...|:.|
Human   430 RQ-RQKCLESQRQNNQETPNLKLSPCAKVKGEDAKSQVWAFTYTQQILQEELCLSVITLFPGAPV 493

  Fly   574 VLKACDDSENQRWIMREGGLVRHYKINVCLDS---RDQSQQG--VSAQHCNSALGTQRW 627
            ||..|.:.::::...:.|..:.|...::|||:   .|.::.|  :....|.|:|.:|.|
Human   494 VLVLCKNGDDRQQWTKTGSHIEHIASHLCLDTDMFGDGTENGKEIVVNPCESSLMSQHW 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	198/294 (67%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	36/131 (27%)
GALNT14	NP_001240755.1	pp-GalNAc-T	119..413	CDD:133004	198/294 (67%)
		beta-trefoil_Ricin-like	418..557	CDD:483949	37/136 (27%)