DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt14

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001072369.1	Gene:	galnt14 / 779822	XenbaseID:	XB-GENE-992201	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	500	Identity:	267/500 - (53%)
Similarity:	347/500 - (69%)	Gaps:	23/500 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 EYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIIT 209
            :.|:|..|:.|...|.|||||....|||..|:.:||:|.|.|||:..|....|:.|||.||||||
Frog    54 DQFDERRYLNAQKWRPGEDPYRLYAFNQRESERIPSDRAIKDTRHYRCTELHYQSDLPPTSVIIT 118

  Fly   210 FHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKIDKVRVIRNDKRE-GLVRS 273
            |||||||||||||.|||||:|.|||.||:||||:||:.:|...|:|:.|||.:||::|| ||:||
Frog   119 FHNEARSTLLRTIRSVLNRTPMHLIHEILLVDDFSDNLDDCRLLSKLPKVRCLRNEQREAGLIRS 183

  Fly   274 RVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRG 338
            ||:||..|.::||||||||.|.|:.||.|||.|::|||||||.||||:|::|.|.||.||:||||
Frog   184 RVRGAGVAQAAVLTFLDSHCEVNKDWLPPLLHRIKEDPTRVVSPVIDIINLDTFAYIAASSDLRG 248

  Fly   339 GFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLE 403
            ||||:|.||||.||..::|.| .|||..|:||:||||||||:|::||.|||||..||:|||||.|
Frog   249 GFDWSLHFKWEQLSAEQKAKR-LDPTEPIKTPVIAGGLFVIEKSWFNHLGKYDTAMDIWGGENFE 312

  Fly   404 ISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPL 468
            ||||||.|||||||||||||||||||:|||.||.|:.|.:.:||:|.||||||::|.|||.|.|.
Frog   313 ISFRVWMCGGSLEIIPCSRVGHVFRKKHPYVFPEGNANTYIKNTKRTAEVWMDEFKNHYYAARPA 377

  Fly   469 AKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAP--DPQEVGQFRQDSTECLDTMGHLIDG 531
            |:..|:|:|..||:|:..|.|:.||||||||||:||.|  ...:.|..|| ...|:::  ...:|
Frog   378 AQGRPYGDIQKRLSLRRTLKCRSFKWYLENVYPELQIPAESLSKSGIIRQ-RQRCIES--QKTEG 439

  Fly   532 ----TVGIFPCHNTGG----NQEWAFTKRGEIKHDDLCLTLVTFARGSQVVLKACDDSE-NQRWI 587
                ::.:.||.:..|    :|||.:|:..:|....||:::.|...|:||||..|.:.: .|||
Frog   440 PEPPSLNLVPCSSLKGVSPQSQEWVYTQVQQISQGPLCMSVHTLFPGTQVVLLPCREGDGKQRW- 503

  Fly   588 MREGGLVRHYKINVCLDS-----RDQSQQGVSAQHCNSALGTQRW 627
            .:.|..:.|.....|||:     .::|:: :....|.:...||||
Frog   504 SKVGSHIEHMASRFCLDTDIIGDTEESRE-IVINPCETTAITQRW 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	164/232 (71%)
		pp-GalNAc-T	205..500	CDD:133004	198/295 (67%)
		Ricin_B_lectin	511..627	CDD:279046	34/129 (26%)
		RICIN	513..629	CDD:238092	34/128 (27%)
galnt14	NP_001072369.1	Abhydrolase	1..>78	CDD:304388	10/23 (43%)
		Glyco_tranf_2_3	111..338	CDD:290369	160/227 (70%)
		pp-GalNAc-T	114..409	CDD:133004	198/295 (67%)
		Ricin_B_lectin	422..547	CDD:279046	34/129 (26%)
		RICIN	423..549	CDD:238092	35/129 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351893at33208
OrthoFinder	1	1.000	-	-		FOG0001204
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010