DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Galntl5

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_080725.2	Gene:	Galntl5 / 67909	MGIID:	1915159	Length:	431	Species:	Mus musculus

Alignment Length:	358	Identity:	154/358 - (43%)
Similarity:	225/358 - (62%)	Gaps:	20/358 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 NGEDPYI-----RNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLL 219
            |..||.:     |...|...|..|...|::||:|:.:|:.|.|..:||..|:||.|:||..:|||
Mouse    68 NFSDPELIQGLRRYGLNAIMSRRLGIEREVPDSRDKICQQKHYPFNLPTASIIICFYNEEFNTLL 132

  Fly   220 RTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKID--------KVRVIRNDKREGLVRSRVK 276
            |.:.||:|.||:||:.||:||||.|:.  |.|: .|:|        ||::|||.|||||:||::.
Mouse   133 RAVSSVVNLSPQHLLEEIILVDDMSEF--DDLK-DKLDYYLEIFRGKVKLIRNKKREGLIRSKMI 194

  Fly   277 GADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFD 341
            ||..|...:|.|||||.|.|.:||||||..:.:|...||||:||||:.....|:.|.. :||.||
Mouse   195 GASRASGDILVFLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPI-VRGAFD 258

  Fly   342 WNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISF 406
            |||..:|:.:...| ......|:|.||:|.:.||:|.|::.|||:||:||..||:.||||:|:|.
Mouse   259 WNLNLRWDNVFAYE-LDGPEGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSL 322

  Fly   407 RVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKN 471
            |:|.|||.|.|:||||||:..:....:.  ..:.:..:||..|...||:|:||.:::...|....
Mouse   323 RIWMCGGQLFILPCSRVGYNSKALSQHR--RANQSALSRNLLRVVHVWLDEYKGNFFLQRPSLTY 385

  Fly   472 IPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQ 504
            :..|||.:|:.|:::|.||.|:|||:|::|:|:
Mouse   386 VSCGNISERVELRKRLGCKSFQWYLDNIFPELE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	116/239 (49%)
		pp-GalNAc-T	205..500	CDD:133004	136/302 (45%)
		Ricin_B_lectin	511..627	CDD:279046
		RICIN	513..629	CDD:238092
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		59/112 (53%)
		pp-GalNAc-T	118..414	CDD:133004	136/302 (45%)
		Glyco_tranf_2_2	118..380	CDD:287123	122/268 (46%)
		Catalytic subdomain B	282..344		35/61 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820