Protein Alignment Pgant2 and GALNT17

DIOPT Version :9

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_071924.1
• Gene: GALNT17 / 64409
• HGNCID: 16347
• Length: 598
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 200/550 - (36%)
• Similarity: 292/550 - (53%)
• Gaps: 63/550 - (11%)

  Fly   108 KLNGIVALEETSQGLSGGTGGPG-GRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFN 171
            :|||:    ..|.||..|.||.| |.||...|....|                ..:.|:.:..:|
Human    77 QLNGL----SKSLGLIEGYGGRGKGGLPATLSPAEEE----------------KAKGPHEKYGYN 121

  Fly   172 QEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIRE 236
            ...|:.:..:|.|||.|...|:..||.:|||:.|:|..|.|||.|.:||::.|.:|.:|.||::|
Human   122 SYLSEKISLDRSIPDYRPTKCKELKYSKDLPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKE 186

  Fly   237 IVLVDDYSDHPEDGLELAK-IDK-----VRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVEC 295
            |:||||.||..|..:.|.: :.|     |:|:||.|||||:|:|::|...|...|..|.|:|||.
Human   187 IILVDDNSDEEELKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEF 251

  Fly   296 NEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKW-EYLSPSERAMR 359
            ...|.||:|.|::|:..||:.|.||.|..|||: :....:...|:.|.|   | .|:||.:....
Human   252 TAGWAEPVLSRIQENRKRVILPSIDNIKQDNFE-VQRYENSAHGYSWEL---WCMYISPPKDWWD 312

  Fly   360 HNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVG 424
            ..||:..||||.:.|..||:::.:|.::|..|..|||:||||:|:..:||.||||:|::|||||.
Human   313 AGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVA 377

  Fly   425 HVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNA--VPLAK-NIPFGNIDDRLALKEK 486
            |:.||:.||.  ...|....||..|.|||||||||.|.|.|  :||.. .|..|::.:|.||::.
Human   378 HIERKKKPYN--SNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKS 440

  Fly   487 LHCKPFKWYLENVYPDLQA-PDPQEVGQFRQDSTE--CLDTMGHLIDGTVGIFPCHNTGGNQEWA 548
            |.||.|:|||::|||:::. .:....|:.|.:..:  ||| .|.|.:.|..::|||. .|.|...
Human   441 LKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLD-QGPLENHTAILYPCHG-WGPQLAR 503

  Fly   549 FTKRG----------EIKHDDLCLTLVTFARGSQVVLKACD---DSENQRWIMREGGLVRHYKIN 600
            :||.|          .:..|..||...:.:|..|  |..||   .|..:||...:.|.:.:....
Human   504 YTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQ--LLDCDKVKSSLYKRWNFIQNGAIMNKGTG 566

  Fly   601 VCLDSRDQSQQGVS--AQHCNSALGTQRWS 628
            .||:..::...|:.  .:.|..    |||:
Human   567 RCLEVENRGLAGIDLILRSCTG----QRWT 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	104/238 (44%)
		pp-GalNAc-T	205..500	CDD:133004	133/304 (44%)
		Ricin_B_lectin	511..627	CDD:279046	33/132 (25%)
		RICIN	513..629	CDD:238092	34/132 (26%)
GALNT17	NP_071924.1	Catalytic subdomain A	151..262		50/110 (45%)
		pp-GalNAc-T	155..454	CDD:133004	133/304 (44%)
		Catalytic subdomain B	319..381		31/61 (51%)
		RICIN	467..593	CDD:238092	35/133 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810