DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pgant2 and galnt8a.2

DIOPT Version :9

Sequence 1:NP_608773.2 Gene:Pgant2 / 33556 FlyBaseID:FBgn0031530 Length:633 Species:Drosophila melanogaster
Sequence 2:XP_021326339.1 Gene:galnt8a.2 / 568500 ZFINID:ZDB-GENE-131122-40 Length:609 Species:Danio rerio


Alignment Length:494 Identity:176/494 - (35%)
Similarity:264/494 - (53%) Gaps:72/494 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   147 FNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFH 211
            |.|.||          :.::.||        ||.||.|||||:|.|..|.|.:|||..|||:.:.
Zfish   111 FQEFGY----------NVFLSNR--------LPLNRTIPDTRDPRCSLKIYPKDLPTISVILIYL 157

  Fly   212 NEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAK----IDK-----VRVIRNDKR 267
            |||.|.:.|.:.|:::::|.||::|||||||.|.:.:..|.|.|    |:|     ::.:|:.|:
Zfish   158 NEALSVIKRAVQSIIDKTPAHLLKEIVLVDDNSSNEDLKLPLDKYIDLINKGKPGLIKKVRHKKQ 222

  Fly   268 EGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYI-- 330
            .||.::|:.|.:||...|:..||:|:|.::.|.||||.:::.:.|.|:.||.|.:..|..:.|  
Zfish   223 MGLAKARMSGWEAATGQVVAILDAHIEVHKEWAEPLLAQIKANRTTVLSPVFDKVLFDTLEVIKY 287

  Fly   331 --GASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMK 393
              .|.|     |||:|...:|...|....::  ||:...::|.:. |:.|.|:.:..::|..|..
Zfish   288 NPAAHA-----FDWSLWCMYERFRPEWYKLK--DPSEPGKSPSVM-GILVADREFLGEIGVLDEG 344

  Fly   394 MDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDY 458
            |.::||||:|:..|||.||||:|::|||::.||.|...||: |..| .:..||..|.||:|||:|
Zfish   345 MTIYGGENVELGIRVWLCGGSVEVVPCSKIAHVERAHKPYS-PDLS-KLMIRNALRVAEIWMDEY 407

  Fly   459 KQHYYNAVPLAKNIP-------FGNIDDRLALKEKLHCKPFKWYLENVYPDLQA-PDPQEVGQFR 515
            |.:    |.:|.|:|       .||:.:|..|:|||.|||||||||||||.|.. .|....|..:
Zfish   408 KSN----VNIAWNLPLKDHGIDIGNVTERKQLREKLKCKPFKWYLENVYPLLDRWDDILGYGVLK 468

  Fly   516 QD--STECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEI---------KHDDLCLTLVTFAR 569
            .|  .|.|:| .|.:......:|.||.. |.|...:.:.|||         .:.:.|||  ....
Zfish   469 NDILKTHCID-QGPVPGSVPVLFGCHYY-GPQRCYYKRTGEIYVGSIKSHTYNSNRCLT--DPGS 529

  Fly   570 GSQVVLKACDDSENQ----RWIMREGGLVRHYKINVCLD 604
            ||.|.|..|..::.:    .|...:|..:|:.|.|.|::
Zfish   530 GSTVTLYNCKYAKEKGFSIYWDFTQGKEIRNKKTNRCIE 568

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pgant2NP_608773.2 WcaA 200..>432 CDD:223539 89/244 (36%)
pp-GalNAc-T 205..500 CDD:133004 121/314 (39%)
Ricin_B_lectin 511..627 CDD:279046 28/109 (26%)
RICIN 513..629 CDD:238092 27/107 (25%)
galnt8a.2XP_021326339.1 pp-GalNAc-T 151..452 CDD:133004 121/314 (39%)
RICIN 475..591 CDD:238092 25/98 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3736
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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