DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt17

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_696189.5	Gene:	galnt17 / 567794	ZFINID:	ZDB-GENE-110419-5	Length:	617	Species:	Danio rerio

Alignment Length:	566	Identity:	196/566 - (34%)
Similarity:	289/566 - (51%)	Gaps:	85/566 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 GAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEET----SQGLSGGTG---GPGGRLP 134
            |.....|.|..|...|.|||:  |.:..|.:.|..:.:||:.    ..|||...|   |.|||
Zfish    49 GVGQQMAVDSRGQTNLNGSVQ--ETSITHDVLLKRLGSLEDVVYRQLNGLSKSLGLIEGFGGR-- 109

  Fly   135 VAPSGRG------TEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCR 193
                |||      |..|. .||.::|        :.|..|.|   .||.:..:|.:||.|...|:
Zfish   110 ----GRGGIPATLTPAEE-KEAKFLR--------EKYGYNAF---LSDKISLDRSLPDYRPSKCK 158

  Fly   194 TKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPE-DGLELAKID 257
            ...:..|||:.|:|..|.|||.|.:||::.|.:|.:|.||::||:||||.||..: .|.....::
Zfish   159 KAFFPRDLPQISIIFIFVNEALSVILRSVHSAVNHTPAHLLKEIILVDDNSDDVQLKGPLEEYVN 223

  Fly   258 K-----VRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCP 317
            |     ::::||.|||||:|:|::|...|...|..|.|:|||....|.||:|.|::|:..|::.|
Zfish   224 KRYPGLIKIVRNQKREGLIRARIEGWKVATGEVTGFFDAHVEFTPAWAEPVLSRIKENHKRIILP 288

  Fly   318 VIDVISMDNFQYIGASADLRGGFDWNLIFKW-EYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDK 381
            .||.|..:.|: :....:...|::|.|   | .|:||.::.....|.:..||||.:.|..||:::
Zfish   289 SIDNIKDETFE-LERYENSGHGYNWEL---WCMYISPPKQWWDEGDTSAPIRTPAMIGCSFVVNR 349

  Fly   382 AYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNV---F 443
            .||..||..|..|||:||||:|:..|||.||||:|::|||||.|:.|.:.||     ..|:   .
Zfish   350 EYFGDLGLLDAGMDVYGGENIELGIRVWLCGGSMEVLPCSRVAHIARTKKPY-----HSNIAFHT 409

  Fly   444 ARNTRRAAEVWMDDYKQHYYNAVPLAKNIP-------FGNIDDRLALKEKLHCKPFKWYLENVYP 501
            .||..|.||||||.||.:.|    ||.|:|       :|::.:||||:::|.||.|.|||:|:||
Zfish   410 RRNALRVAEVWMDQYKSNVY----LAWNLPMKNHGIDYGDVSERLALRKRLQCKSFDWYLDNIYP 470

  Fly   502 DLQA-PDPQEVGQFRQDSTE--CLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEI-------- 555
            :::. .:....|:.|..:..  |:| .|...:.|..:.|||. .|.|...:||.|.:
Zfish   471 EMRRYNNTVFYGEIRNTNVTHLCVD-QGIKENHTATLHPCHG-WGPQLGRYTKEGYLFLGPLGST 533

  Fly   556 KHDDLCLT---------LVTFARGSQVVLKACDDSENQRWIMREGG 592
            ..|..|:.         |:...:.|.|..|....::|:..|.|..|
Zfish   534 GEDTRCVVDDKISSYPQLLNCEKVSSVRQKTWHFAQNESIISRATG 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	99/238 (42%)
		pp-GalNAc-T	205..500	CDD:133004	128/311 (41%)
		Ricin_B_lectin	511..627	CDD:279046	24/101 (24%)
		RICIN	513..629	CDD:238092	23/99 (23%)
galnt17	XP_696189.5	pp-GalNAc-T	170..469	CDD:133004	128/311 (41%)
		Ricin_B_lectin	480..605	CDD:279046	24/102 (24%)
		RICIN	482..607	CDD:238092	24/100 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810