DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt12

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_688194.1	Gene:	galnt12 / 559736	ZFINID:	ZDB-GENE-060503-704	Length:	578	Species:	Danio rerio

Alignment Length:	519	Identity:	219/519 - (42%)
Similarity:	308/519 - (59%)	Gaps:	46/519 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 GRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYRE-DLP 202
            ||..:::...|       ..|..|:...:::.|...||.:..:|.:.:..||:||..||.. .||
Zfish    74 GRAVKLDLSGE-------EKREEEESIKKHQINTYVSDRISLHRRLAERWNPLCRNLKYDYLSLP 131

  Fly   203 ETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSD--HPEDGLE--LAKIDKVRVIR 263
            .|||:|.|:|||.||||||:.|||..||:.|:.|::|||||||  |.::.||  :|.:.|||:||
Zfish   132 TTSVVIAFYNEAWSTLLRTVHSVLETSPDLLLNEVILVDDYSDREHLKEPLENYIADLKKVRLIR 196

  Fly   264 NDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQ 328
            ..|||||||:|:.||..|...||||||.|.||:|.||||||:|::|:|:.|||||||||..:.||
Zfish   197 ARKREGLVRARLLGASIATGEVLTFLDCHCECHEGWLEPLLQRIKEEPSAVVCPVIDVIDWNTFQ 261

  Fly   329 YIGASADLR-GGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDM 392
            |:|...:.: |||||.|:|.|..: |.....|.:..|..:|:|.:|||||.::|.||..||.||.
Zfish   262 YLGNPGEPQIGGFDWRLVFTWHSI-PEHEQKRRSAATDVVRSPTMAGGLFAVNKKYFLYLGTYDT 325

  Fly   393 KMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDD 457
            .|:||||||||.|||:|||||||||.|||.|||||.|:.||     |.|....|:.|||||||||
Zfish   326 GMEVWGGENLEFSFRIWQCGGSLEIHPCSHVGHVFPKKAPY-----SRNKALANSVRAAEVWMDD 385

  Fly   458 YKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPD--PQEVGQFRQD--S 518
            :|:.||:..|.|:...:|::.||..|:.:|.||.|:|:|:|:|||:|.|:  |...|..:..  :
Zfish   386 FKEVYYHRSPHARLEAYGDVTDRRKLRMRLRCKDFRWFLDNIYPDIQVPEDKPGMFGMLKNKGMT 450

  Fly   519 TECLD--------TMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHD--DLCLTLVTFARGSQV 573
            ..|.|        ..||    .|.::|||..|.||.:.::...||:::  |....:|.....:.:
Zfish   451 NYCFDYNPPDEHKIAGH----RVILYPCHGMGQNQFFEYSTLQEIRYNTRDPAGCVVADPVSTFL 511

  Fly   574 VLKACDD-----SENQRWIMREGGLVRHYKINVC---LDSRDQSQQGVSAQHCNSALGTQRWSF 629
            .:..|..     .|:|:::.||.|.:.|.:...|   :|..|....|.:.:.|:.: ..|:|.|
Zfish   512 TMNLCSKPREAVPEDQKFLFREDGSLYHVQTQKCVEAVDRTDAGSPGPALRPCSDS-DAQKWFF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	137/236 (58%)
		pp-GalNAc-T	205..500	CDD:133004	164/299 (55%)
		Ricin_B_lectin	511..627	CDD:279046	29/135 (21%)
		RICIN	513..629	CDD:238092	29/135 (21%)
galnt12	XP_688194.1	pp-GalNAc-T	134..428	CDD:133004	164/299 (55%)
		Ricin_B_lectin	440..572	CDD:279046	29/136 (21%)
		RICIN	442..574	CDD:238092	30/136 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820