DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt11

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001070030.2	Gene:	galnt11 / 558716	ZFINID:	ZDB-GENE-060929-998	Length:	590	Species:	Danio rerio

Alignment Length:	652	Identity:	239/652 - (36%)
Similarity:	324/652 - (49%)	Gaps:	146/652 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VFVSIIWMFVMVYYFQSSTEKVENRALRLREVATAMQ-QYQDDSSSAAAASTARQWAPAGGGAGP 72
            :|.|:.|..::..||..|.|.    .|..|.|....| ::|                       |
Zfish    14 LFTSVTWSILLFLYFNLSQES----RLSFRNVPVQGQHRFQ-----------------------P 51

  Fly    73 GAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEETSQGLSGGTGGPGGRLPVAP 137
            ....|.|....|   |:.:..|.                  |||.....||.
Zfish    52 RFTRGPAVQHRD---GSQVRKGQ------------------ALEAVKPDLSP------------- 82

  Fly   138 SGRGTEVEYFNEAGYIRAGALRNGEDP------YIRNRFNQEASDALPSNRDIPDTRNPMCRTKK 196
                            ..|.:.|.:|.      |.::.||...|:.|..:||:||||...||.:.
Zfish    83 ----------------ELGMIFNKQDQEVRDMGYHKHAFNVLISNRLGYHRDVPDTRTDKCRDRA 131

  Fly   197 YREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYS--DHPEDGLE------L 253
            |...||..|::|.|.|||.|.||||:.|||:|:|.:|:.||:||||:|  |..::.|:      |
Zfish   132 YSVSLPTASIVICFFNEAFSALLRTVHSVLDRTPNYLLHEIILVDDHSELDDLKEDLDSYVQQHL 196

  Fly   254 AKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPV 318
            .|  ||:|:||:|||||:|.|:.||..|...||.|||||.|.||.||:|||..::|:...|||||
Zfish   197 QK--KVKVVRNEKREGLIRGRMIGASHATGEVLVFLDSHCEVNEAWLQPLLTPIKENRKTVVCPV 259

  Fly   319 IDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAY 383
            ||:||.|...|. .|..:||||:|.|.|||:.:..||.    |.|..|||:|.:|||||.:|:.|
Zfish   260 IDIISADTLVYT-PSPIVRGGFNWGLHFKWDPVPMSEL----NSPDGAIRSPTMAGGLFAMDRNY 319

  Fly   384 FNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTR 448
            |.:||:||..||:|||||||||||:|.|||.|.|:|||||||:||||.||..|||. :..|.|:.
Zfish   320 FYELGQYDRGMDIWGGENLEISFRIWMCGGQLLIVPCSRVGHIFRKRRPYGSPGGQ-DTMAHNSL 383

  Fly   449 RAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDPQEVGQ 513
            |.|.|||||||:.|:...|..:|..:|:|.:|::::::|.|..|||||:|:||::|...|.:..|
Zfish   384 RLAHVWMDDYKEQYFALRPELRNRDYGDISERVSIRKRLQCHSFKWYLDNIYPEMQVSSPHKPQQ 448

  Fly   514 FRQDSTECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKH--DDLCLTLVTFARGSQ---- 572
                                   |.....|.:.....:||.:::  .|.|  ||...|.||
Zfish   449 -----------------------PVFINKGLKRPKVLQRGRLRNLLADKC--LVAQGRPSQKGGA 488

  Fly   573 VVLKACDDSE-NQRWIMRE------GGLVRHYKINVCLD-SRDQSQQGVSAQHCNSALGTQRWSF 629
            ||:|.||..: .|.|...|      .||       :||| |..:|........|:.:.|:|:|:.
Zfish   489 VVVKDCDPQDPEQEWAYDEEHELVLAGL-------LCLDMSEIRSSDPPRLMKCHGSGGSQQWTL 546

  Fly   630 GK 631
            ||
Zfish   547 GK 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	132/239 (55%)
		pp-GalNAc-T	205..500	CDD:133004	160/302 (53%)
		Ricin_B_lectin	511..627	CDD:279046	30/129 (23%)
		RICIN	513..629	CDD:238092	31/129 (24%)
galnt11	NP_001070030.2	GT2	135..468	CDD:224137	171/363 (47%)
		pp-GalNAc-T	140..435	CDD:133004	160/302 (53%)
		Ricin_B_lectin	465..586	CDD:279046	29/93 (31%)
		RICIN	465..586	CDD:238092	29/93 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820