DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt6

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_998361.1	Gene:	galnt6 / 406477	ZFINID:	ZDB-GENE-040426-2272	Length:	619	Species:	Danio rerio

Alignment Length:	524	Identity:	226/524 - (43%)
Similarity:	305/524 - (58%)	Gaps:	38/524 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 PVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDI-PDTRNPMCRTKKY 197
            |.||...|...:|    ..:.....:..::...|:.|||.|||.:..:|.: .|||.|.|..:|:
Zfish   105 PQAPGADGVPFQY----DRMTKEEEKEKQEGMTRHCFNQFASDRISLHRTLGDDTRPPECVDRKF 165

  Fly   198 RE--DLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYS--DHPEDGLE--LAKI 256
            |.  .||.|||||.|||||.||||||:.|||:.||...::||::|||.|  :|....||  :..:
Zfish   166 RRCPALPTTSVIIVFHNEAWSTLLRTVYSVLHTSPAAFLKEIIMVDDASTAEHLHGKLEEYVKAL 230

  Fly   257 DKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDV 321
            ..|:|:|..:|:||:.:|:.||..|...:|||||:|.||...||||||.|:.|:||.||.|.|..
Zfish   231 KIVKVVRQPERKGLITARLLGASKAEGEILTFLDAHCECFHGWLEPLLARIVEEPTAVVSPEITT 295

  Fly   322 ISMDNFQY----IGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKA 382
            |.::.||:    ..|.|..||.|||:|.|.||.:...|.|.| .|.|..::||..|||||.|.||
Zfish   296 IDLNTFQFHKPVATARAHNRGNFDWSLTFGWEGIPDYENAKR-KDETYPVKTPTFAGGLFSISKA 359

  Fly   383 YFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNT 447
            ||.|:|.||.||::|||||:|:|||||||||.|||||||.||||||.:.|:|||.|: .|..||.
Zfish   360 YFEKIGTYDDKMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGT-EVITRNQ 423

  Fly   448 RRAAEVWMDDYKQHYY----NAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPD- 507
            .|.|||||||||..:|    :|..:||...||:|.|||.|:|.|.||.|.|||.||||:...||
Zfish   424 VRLAEVWMDDYKLIFYRRSQSAAKMAKEKGFGDISDRLKLREDLQCKNFSWYLSNVYPEAFVPDL 488

  Fly   508 -PQEVGQFR-QDSTECLDTMGHLIDG--TVGIFPCHNTGGNQEWAFTKRGEIKHD---DLCLTLV 565
             |.:.|..: :.:.:||| :|...:|  .|.::.|||.||||.:.:|...|::|:   .|||...
Zfish   489 SPVKFGALKNRGAQQCLD-VGESNNGGKPVIMYTCHNMGGNQYFEYTSHKELRHNIGKQLCLQAS 552

  Fly   566 TFARGSQVVL-----KACDDSENQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQHCNSALGTQ 625
            .:....::.|     |....:..|.|::.|..|:::.....||..:...   :....||.....|
Zfish   553 PYPEPVKIELCTLKGKGSSLAPEQEWLITEEQLLKNPSSGKCLHKKGDK---ILMSPCNPDDHHQ 614

  Fly   626 RWSF 629
            :|:|
Zfish   615 QWAF 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	129/239 (54%)
		pp-GalNAc-T	205..500	CDD:133004	164/306 (54%)
		Ricin_B_lectin	511..627	CDD:279046	31/126 (25%)
		RICIN	513..629	CDD:238092	31/126 (25%)
galnt6	NP_998361.1	pp-GalNAc-T	175..480	CDD:133004	164/306 (54%)
		Ricin_B_lectin	493..616	CDD:279046	31/126 (25%)
		RICIN	494..618	CDD:238092	32/127 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820