DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Galnt16

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001094333.1	Gene:	Galnt16 / 362760	RGDID:	1310202	Length:	558	Species:	Rattus norvegicus

Alignment Length:	527	Identity:	272/527 - (51%)
Similarity:	353/527 - (66%)	Gaps:	31/527 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 SGGTGG--PGGR---------LPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASD 176
            |||.|.  .|||         :|:..:  ||..:.|:|..|:.|..|:.|||||.::.|||..||
  Rat    35 SGGRGAQRAGGRPEQLREDRTIPLIVT--GTPSKGFDEKAYLSAKQLKPGEDPYRQHAFNQLESD 97

  Fly   177 ALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVD 241
            .|..:|.|.|||:..|.:..|..|||.||||||||||||||||||:.|||||:|..||:||:|||
  Rat    98 KLSPDRPIRDTRHYSCPSLSYSSDLPATSVIITFHNEARSTLLRTVKSVLNRTPAGLIQEIILVD 162

  Fly   242 DYSDHPEDGLELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLER 306
            |:|..|||.|.|.:|.||:.:||||||||:||||:|||.|.:|||||||||.|.|..||:|:|:|
  Rat   163 DFSSDPEDCLLLTRIPKVKCLRNDKREGLIRSRVRGADVAGASVLTFLDSHCEVNVEWLQPMLQR 227

  Fly   307 VREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPM 371
            |.||.||||.|:|||||:|||.|:.|||||||||||:|.||||.: |.|:.|...|||..||||:
  Rat   228 VMEDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQI-PLEQKMTRTDPTKPIRTPV 291

  Fly   372 IAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFP 436
            ||||:|||||::||.|||||.:||:|||||.|:|||||.|||||||:|||||||||||||||.||
  Rat   292 IAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFP 356

  Fly   437 GGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYP 501
            .|:...:.|||:|.||||||:|||:||.|.|.|....||::..|:..::|:.||.|:||||||||
  Rat   357 EGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAIGKAFGSVATRIEQRKKMDCKSFRWYLENVYP 421

  Fly   502 DLQAPDPQEVGQFRQDSTECLDTMGHLIDG--TVGIFPCHNTGGN----QEWAFTKRGEIKHDDL 560
            :|..|..:.:....:....||::.|....|  .:|:..|..:..:    |.|.|:.. .|:....
  Rat   422 ELTVPVKEVLPGVIKQGVNCLESQGQNTAGDLLLGMGICRGSAKSPPPAQAWLFSDH-LIQQQGK 485

  Fly   561 CL----TLVTFARGSQVVLKACDDSE-NQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQHCNS 620
            ||    ||:: :.||.|||::|:..| .|:| .|:|..::|....:||:::...   :....|.:
  Rat   486 CLAATSTLMS-SPGSPVVLQSCNPKEGKQKW-RRKGSFIQHSVSGLCLETKPAQ---LVTNKCQA 545

  Fly   621 ALGTQRW 627
            ....|:|
  Rat   546 DAQAQQW 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	167/231 (72%)
		pp-GalNAc-T	205..500	CDD:133004	199/294 (68%)
		Ricin_B_lectin	511..627	CDD:279046	30/126 (24%)
		RICIN	513..629	CDD:238092	31/126 (25%)
Galnt16	NP_001094333.1	pp-GalNAc-T	126..420	CDD:133004	199/294 (68%)
		WcaA	126..>222	CDD:223539	68/95 (72%)
		Ricin_B_lectin	441..543	CDD:279046	28/107 (26%)
		RICIN	441..543	CDD:238092	28/107 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351893at33208
OrthoFinder	1	1.000	-	-		FOG0001204
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2085
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820