Protein Alignment Pgant2 and Galntl6

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001129228.1
• Gene: Galntl6 / 361142
• RGDID: 1564773
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 197/519 - (37%)
• Similarity: 288/519 - (55%)
• Gaps: 51/519 - (9%)

  Fly   153 IRAGALRNG----------------EDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDL 201
            |:..|||:|                :..|..|.||...|:.:...|.:||.|:..|:.|.|.|.|
  Rat    75 IQKDALRSGKGEHGKPYPLTEEDHDDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERL 139

  Fly   202 PETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSD--HPEDGLE--LAKIDKVRVI 262
            |.||:||.||||..::|||||.|::||:||.||.||:||||:||  |.:|.||  :|:...||::
  Rat   140 PNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDKLEDYMARFPIVRIV 204

  Fly   263 RNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNF 327
            |..|||||:|:|:.||..|...||||||||.|.|..||.|||.::..:...:|||:||||...:|
  Rat   205 RTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHSHF 269

  Fly   328 QYIGASAD-LRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYD 391
            .|...:.| :||.|||.:.:|...:.|.   ::..||:....:|::|||||.:|:.:|.:||.||
  Rat   270 GYEAQAGDAMRGAFDWEMYYKRIPIPPE---LQRADPSEPFESPVMAGGLFAVDRKWFWELGGYD 331

  Fly   392 MKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMD 456
            ..:::||||..||||:||.|||.:..:|||||||::||..||..|  ||...|||.:|.||.|||
  Rat   332 PGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVP--SGTSLARNLKRVAETWMD 394

  Fly   457 DYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENV-------YPDLQAPDPQEVGQF 514
            ::.::.|...|..:::..|:|..:..|:::|.||.|||::..|       ||.:: |.|...|:.
  Rat   395 EFAEYIYQRRPEYRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYPPVE-PLPAAWGEI 458

  Fly   515 RQDSTE-CLDTMGHLIDGTVGIFPCHNTGGNQEWA----FT-------KRGEIKHD-DLCLTLVT 566
            |..:.. |:|:....:...:.:..|...|..:.|:    ||       :.||..|. ..||..:
  Rat   459 RNVAANLCVDSKHGAMGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCLDAI- 522

  Fly   567 FARGSQVVLKACDDSE-NQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQHCNSALGTQRWSF 629
             :..|.|.|..|...: ||.|..||...:.|...|.|:|. :.:::.|....|:....||:|.|
  Rat   523 -SHSSPVTLYDCHGMKGNQLWGYREDRTLFHPVSNSCMDC-NPAEKKVFMARCDPLSETQQWMF 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	139/306 (45%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	32/132 (24%)
Galntl6	NP_001129228.1	pp-GalNAc-T	143..438	CDD:133004	138/299 (46%)
		beta-trefoil_Ricin_GALNTL6	449..594	CDD:467355	35/140 (25%)