DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Galnt14

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001012109.1	Gene:	Galnt14 / 313878	RGDID:	1310068	Length:	552	Species:	Rattus norvegicus

Alignment Length:	497	Identity:	271/497 - (54%)
Similarity:	350/497 - (70%)	Gaps:	17/497 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 EYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIIT 209
            |.|:|..|:.|...|.|:|||....|||..|:.:.|||.:||||:..|....|..|||.||:|||
  Rat    54 EQFDERRYLNAKKWRVGDDPYKLYAFNQRESERISSNRAVPDTRHKRCSLLVYCTDLPPTSIIIT 118

  Fly   210 FHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKIDKVRVIRNDKREGLVRSR 274
            |||||||||||||.|||||:|.|||:||:||||:|:.|||..:|.|:.||:.:||.:|:||||||
  Rat   119 FHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNSERQGLVRSR 183

  Fly   275 VKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGG 339
            ::|||.|..:.|||||||.|.|..||:|||.||:||.|||||||||:|::|.|.||.::::||||
  Rat   184 MRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFNYIESASELRGG 248

  Fly   340 FDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEI 404
            |||:|.|:||.||..::|:| .|||..||||:|||||||||||:|:.|||||:.||:|||||.||
  Rat   249 FDWSLHFQWEQLSVEQKALR-LDPTEPIRTPIIAGGLFVIDKAWFDYLGKYDVDMDIWGGENFEI 312

  Fly   405 SFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLA 469
            |||||.|||.|||||||||||||||:|||.||.|:.|.:.:||:|.||||||:|||:||.|.|.|
  Rat   313 SFRVWMCGGGLEIIPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFA 377

  Fly   470 KNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDPQEV--GQFRQDSTECLDTMGHLIDGT 532
            ...|||||::||.|::.|||:.||||||||||:|:.|....:  |..|| ..:||::.......|
  Rat   378 LERPFGNIENRLNLRKNLHCQTFKWYLENVYPELRVPPDSSIQKGNIRQ-RQKCLESQKQKNQET 441

  Fly   533 --VGIFPCHNTGG----NQEWAFTKRGEIKHDDLCLTLVTFARGSQVVLKAC-DDSENQRWIMRE 590
              :.:.||....|    :|.||||...:|..::|||::||...|:.|||..| :..|.|:| .:.
  Rat   442 PHLRLSPCAKVKGDRAKSQVWAFTYTQQIIQEELCLSVVTLFPGAPVVLVLCKNGDERQQW-TKT 505

  Fly   591 GGLVRHYKINVCLDS---RDQSQQG--VSAQHCNSALGTQRW 627
            |..:.|...::|||:   .|.::.|  |....|.|:|.:|.|
  Rat   506 GARIEHIASHLCLDTDMFGDSTEDGKEVVVNPCESSLMSQHW 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	160/231 (69%)
		pp-GalNAc-T	205..500	CDD:133004	198/294 (67%)
		Ricin_B_lectin	511..627	CDD:279046	40/129 (31%)
		RICIN	513..629	CDD:238092	40/127 (31%)
Galnt14	NP_001012109.1	Glyco_tranf_2_3	111..337	CDD:290369	156/226 (69%)
		pp-GalNAc-T	114..408	CDD:133004	198/294 (67%)
		RICIN	422..549	CDD:238092	41/128 (32%)
		Ricin_B_lectin	422..547	CDD:279046	40/126 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351893at33208
OrthoFinder	1	1.000	-	-		FOG0001204
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820