Protein Alignment Pgant2 and Galnt12

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001413928.1
• Gene: Galnt12 / 313233
• RGDID: 1562001
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 233/541 - (43%)
• Similarity: 320/541 - (59%)
• Gaps: 56/541 - (10%)

  Fly   126 TGGPGGRLPVAP---------SGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSN 181
            |..||...||.|         ..:|..|..     .::...||..|:...|::.|...||.:..:
  Rat    50 TPHPGRHEPVLPRPPLPADALGAKGEAVRL-----QLQGEELRLQEESVQRHQINIYLSDRISLH 109

  Fly   182 RDIPDTRNPMCRTKKYRED-LPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSD 245
            |.:|:..||:||..||..| ||:|||:|.|:|||.||||||:.|||..||:.|:.|::|||||||
  Rat   110 RRLPERWNPLCREVKYDYDNLPKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSD 174

  Fly   246 --HPEDGL--ELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLER 306
              |.::.|  ||:::.|||:||..|||||||:|:.||.||...||||||.|.||:|.||||||:|
  Rat   175 REHLKEPLANELSQLPKVRLIRASKREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQR 239

  Fly   307 VREDPTRVVCPVIDVISMDNFQYIGASADLR-GGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTP 370
            :.|..:.|||||||||..:.|:|:|.|.:.: |||||.|:|.|..:...||.:..: |...||:|
  Rat   240 IHEKESAVVCPVIDVIDWNTFEYLGNSGEPQIGGFDWRLVFTWHVVPQRERKLMRS-PIDVIRSP 303

  Fly   371 MIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTF 435
            .:|||||.:.|.||..||.||..|:||||||||.|||:|||||:||..|||.|||||.|:.||
  Rat   304 TMAGGLFAVSKRYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQAPY-- 366

  Fly   436 PGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVY 500
               |.:....|:.|||||||||:|:.||:..|.|:..|||::.:|..|:.||.||.|||:|:.||
  Rat   367 ---SRSKALANSVRAAEVWMDDFKELYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLDTVY 428

  Fly   501 PDLQAPD--PQEVGQFRQDSTE--CLD--------TMGHLIDGTVGIFPCHNTGGNQEWAFTKRG 553
            |:|..|:  |...|........  |||        ..||    .|.::.||..|.||.:.:|.|.
  Rat   429 PELHVPEDRPGFFGMLENRGLRGYCLDYNPPSENNVEGH----QVLLYLCHGMGQNQFFEYTSRQ 489

  Fly   554 EIKHD----DLCLTLVTFARGSQV-VLKACDDS--ENQRWIMREGGLVRHYKINVCLDSRDQSQQ 611
            ||:::    :.|:.:   ..|..| ::..|.|:  |||.::::|.|.:.|.:...|:::.::...
  Rat   490 EIRYNTRQPEACIAV---EEGKDVLIMDLCKDTVPENQEFVLQEDGTLVHKQSGKCVEATEKEFD 551

  Fly   612 GVSAQH---CNSALGTQRWSF 629
            ...|.|   |:|: ..|||.|
  Rat   552 TSFAPHLRDCSSS-DNQRWLF 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	164/299 (55%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	35/138 (25%)
Galnt12	NP_001413928.1	None