DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant2 and Galnt9

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001116116.1	Gene:	Galnt9 / 304571	RGDID:	1311523	Length:	604	Species:	Rattus norvegicus

Alignment Length:	663	Identity:	224/663 - (33%)
Similarity:	336/663 - (50%)	Gaps:	112/663 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RNIKLIVFVSIIWMFVMVYYFQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTARQWAPAG 67
            |.||.::.|:|: :||.:..| |...::::|:..|.:|.....:...:..|.|:|.|.|:
  Rat     5 RKIKTLLTVNIL-VFVGIILF-SVYCRLQDRSEALVQVVRGADRRMRNRLSKASALTDRE----- 62

  Fly    68 GGAGPGAAAGAAGSGADDPGGNVIL--IGSVKDFERNAVHGL-KLNGIVALEETSQGLSGGTGGP 129
                                  .||  :..:::...|.::|| |..|:|      :| .||.|..
  Rat    63 ----------------------AILQRLDHLEEVVYNQLNGLAKPIGLV------EG-PGGLGQG 98

  Fly   130 GGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRT 194
            |....:....:.||.: |.:.||                  |.:.||.:..:|.|||.|...||.
  Rat    99 GVAATLQDDSQETEGK-FEDFGY------------------NAQLSDRISLDRTIPDYRPKRCRQ 144

  Fly   195 KKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAK-IDK 258
            ..|.||||:.||:..|.|||.|.:||::.||:|.:|..|::||:||||.||:.|....|.: :.|
  Rat   145 ITYSEDLPQISVVFIFVNEALSVILRSVHSVVNHTPSQLLKEIILVDDNSDNVELKFNLDQYVHK 209

  Fly   259 -----VRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPV 318
                 |:|:||.:||||:|:|::|...|.:.::.|.|:|||.|..|.||.|.|::||..|::.|.
  Rat   210 RYPGLVKVVRNSRREGLIRARLQGWKVATAPIVGFFDAHVEFNTGWAEPALARIQEDRRRIILPA 274

  Fly   319 IDVISMDNF---QYIGASADLRGGFDWNLIFKW-EYLSPSERAMRHNDPTTAIRTPMIAGGLFVI 379
            ||.|....|   ||..|:    .|::|.|   | .|:.|.:..:...|.:..||||.:.|..||:
  Rat   275 IDNIKYSTFEVQQYASAA----HGYNWGL---WCMYIIPPQDWLDRGDESAPIRTPAMIGCSFVV 332

  Fly   380 DKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFA 444
            |:.||..:|..|..|:|:|.||:|:..||||||||:|::|||||.|:.|.:.||   ....:.:|
  Rat   333 DREYFGDIGLLDPGMEVYGAENIELGMRVWQCGGSMEVLPCSRVAHIERTKKPY---NNDIDYYA 394

  Fly   445 -RNTRRAAEVWMDDYKQHYYNA--VPLAK-NIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQA 505
             ||..|||||||||:|.|.|.|  :|:.. .:.||::.:||||::||.|:.||||||||||:::.
  Rat   395 KRNALRAAEVWMDDFKSHVYMAWNIPMTNPGVDFGDVSERLALRQKLKCRSFKWYLENVYPEMRI 459

  Fly   506 -PDPQEVGQFRQD--STECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIK----------H 557
             .:....|:.|..  |..||| .|...|....::|||.. .:|...::..|.::          .
  Rat   460 YNNTLTYGEVRNSKASGYCLD-QGAEDDDRAILYPCHGM-SSQLVRYSADGLLQLGPLGSTAFLP 522

  Fly   558 DDLCLTLVTFARGSQVVLKACDD--SENQR-WIMREGGLVRHYKINVCLD---SRDQSQQGVS-- 614
            |..|  ||...||....||.|:|  ...|| |...:.|.:.......||:   |:| :..|:.
  Rat   523 DSKC--LVDDGRGRMPTLKKCEDVARPTQRLWDFTQSGPIVSRDTGRCLEVEMSKD-ANFGLRLV 584

  Fly   615 AQHCNSALGTQRW 627
            .|.|:.    |:|
  Rat   585 VQRCSG----QKW 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	103/241 (43%)
		pp-GalNAc-T	205..500	CDD:133004	135/308 (44%)
		Ricin_B_lectin	511..627	CDD:279046	35/135 (26%)
		RICIN	513..629	CDD:238092	35/135 (26%)
Galnt9	NP_001116116.1	pp-GalNAc-T	155..454	CDD:133004	135/308 (44%)
		Ricin_B_lectin	465..593	CDD:279046	35/136 (26%)
		RICIN	467..595	CDD:238092	36/136 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810