DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Galnt13

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_036018146.1	Gene:	Galnt13 / 271786	MGIID:	2139447	Length:	613	Species:	Mus musculus

Alignment Length:	663	Identity:	259/663 - (39%)
Similarity:	355/663 - (53%)	Gaps:	99/663 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRRNI--KLIVFVSIIWMFVMVY---YFQSSTEKVENRALR-----LREVATAMQQYQDDSSSAA 55
            |||.:  |:::..|::|:.|.|:   || |...|.:::..|     ||.|.:..|:
Mouse     1 MRRFVYCKVVLATSLMWVLVDVFLLLYF-SECNKCDDKKERSLLPALRAVISRNQE--------- 55

  Fly    56 AASTARQWAPAGGGAGPGAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLN-------GIV 113
                           |||..            |..:||  .||.:.......|:|       .::
Mouse    56 ---------------GPGEM------------GKAVLI--PKDDQEKMKELFKINQFNLMASDLI 91

  Fly   114 ALEETSQGLSGGTGGPGGRLP-VAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDA 177
            ||..:.         |..||. ....||..|::...:..|.|.         ||...|.......
Mouse    92 ALNRSL---------PDVRLEGQYCCGRCEELQTMQQERYARV---------YISTNFCSSILFW 138

  Fly   178 LPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDD 242
            |..|.::      .|:||.|.::||.|||:|.|||||.||||||:.||:||||.:|:.|::||||
Mouse   139 LKCNTEL------RCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDD 197

  Fly   243 YSDHPEDGLELAKIDK-----VRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEP 302
            .|:.....|.|....|     |::||.::|.||:|:|::||.|:...|:||||:|.||...||||
Mouse   198 ASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEP 262

  Fly   303 LLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAI 367
            ||.|::||...||||:|||||.|.|:|:..|....|||:|.|.|:|..:...|...|..|.|..:
Mouse   263 LLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPV 327

  Fly   368 RTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHP 432
            |||.:|||||.||:.||.::|.||..||:|||||||:|||:|||||||||:.||.|||||||..|
Mouse   328 RTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATP 392

  Fly   433 YTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLE 497
            ||||||:|:|..:|.||.||||||::|..:|...|....:.:|::..|..|:|.|.||||.||||
Mouse   393 YTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLE 457

  Fly   498 NVYPDLQAPDP-QEVGQFRQ-DSTECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHDDL 560
            |:|||.|.|.. ..:|:.|. ::.:|||.||...:..||||.||..||||.:::|...||:.|||
Mouse   458 NIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDL 522

  Fly   561 CLTLVTFARGSQVVLKACDDSENQRWIMREGGLVRHYKINV----CLD--SRDQSQQGVSAQHCN 619
            ||. |:...|..::||......||.|   |.....|..:::    ||.  ..:...|.:|.:.||
Mouse   523 CLD-VSRLSGPVIMLKCHHMRGNQLW---EYDAETHTLVHIITQSCLSMGKGEDGSQDLSMETCN 583

  Fly   620 SALGTQRWSFGKY 632
            .:. .|:|....|
Mouse   584 DST-FQKWLLRNY 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	130/236 (55%)
		pp-GalNAc-T	205..500	CDD:133004	162/299 (54%)
		Ricin_B_lectin	511..627	CDD:279046	41/122 (34%)
		RICIN	513..629	CDD:238092	41/122 (34%)
Galnt13	XP_036018146.1	pp-GalNAc-T	160..460	CDD:133004	162/299 (54%)
Galnt13	XP_036018146.1	Ricin_B_lectin	473..590	CDD:395527	41/121 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820