DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Pgant4

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	195/551 - (35%)
Similarity:	285/551 - (51%)	Gaps:	62/551 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 GGRLPVAPSGRGTEVEYF--NEAGYIRAGALRNG-----EDP---------YIRNRFNQEASDAL 178
            |.||| .|.|...:...:  .||...|:|...:|     |:|         |..|.||...||.:
  Fly    91 GFRLP-EPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRI 154

  Fly   179 PSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDY 243
            ..||.:||.|...|:|:||...||..|||..|.||..:||||:|.||:||:|..|:::||||||.
  Fly   155 SVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDG 219

  Fly   244 SD-----HP-EDGLELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEP 302
            |:     .| :|.::......|.::||.:|:||:.:|:.||..||..|:.|.|||:|.|..||.|
  Fly   220 SEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPP 284

  Fly   303 LLERVREDPTRVVCPVIDVISMDNFQYIGASAD-LRGGFDWNLIFKWEYLSPSERAMRHNDPTTA 366
            |:|.:..:|....||::|.||.::|.|...:.| .||||||.:::|...:.|.:..    |.:..
  Fly   285 LIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDAL----DKSMP 345

  Fly   367 IRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFR-KR 430
            .|:|::.||||.|:..:|..||.||.::|:||||..|:||::|.|||.|..:|||||.|:|| ..
  Fly   346 YRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPM 410

  Fly   431 HPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLA-KNIPFGNIDDRLALKEKLHCKPFKW 494
            .|...|.|. |..|:|.:|.||||||:|||:.|...|.. .|:..|::..:..::|:|.||.|.|
  Fly   411 KPRGNPRGH-NFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHW 474

  Fly   495 YLENVYPDLQAPDP------------QEVGQFRQDSTECLDTMGHLIDGTVGIFPCHNT----GG 543
            ::..|.||.....|            |.|.    :...|||.||...:..||:|.|.:.    ..
  Fly   475 FMTEVAPDFLVKFPPVEPPSYAAGIIQNVA----NPVYCLDNMGKSTEEAVGMFSCADNRTHPQP 535

  Fly   544 NQEWAFTKRGEIK---HDDLCLTLVTFARGSQVVLKAC-DDSENQRWIM-REGGLVRHYKINV-C 602
            ||.|..:...:::   .|.:||.:......:.|.:.:| ....||.|.. |:...:.|.:.|. |
  Fly   536 NQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRC 600

  Fly   603 LDSRDQSQQGVS---AQHCNSALGTQRWSFG 630
            |:.  ..:.|::   |..|.:....|||.||
  Fly   601 LEG--FVENGIAKVVANSCENGNDRQRWEFG 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	102/239 (43%)
		pp-GalNAc-T	205..500	CDD:133004	126/303 (42%)
		Ricin_B_lectin	511..627	CDD:279046	30/128 (23%)
		RICIN	513..629	CDD:238092	31/128 (24%)
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	101/237 (43%)
		pp-GalNAc-T	181..480	CDD:133004	126/303 (42%)
		Ricin_B_lectin	496..626	CDD:279046	31/135 (23%)
		RICIN	498..628	CDD:238092	33/135 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457050
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60373at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850