Protein Alignment Pgant2 and GALNT3

DIOPT Version :9

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_004473.2
• Gene: GALNT3 / 2591
• HGNCID: 4125
• Length: 633
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 211/494 - (42%)
• Similarity: 294/494 - (59%)
• Gaps: 52/494 - (10%)

  Fly   170 FNQEASDALPSNRDI-PDTRNPMCRTKKYRE--DLPETSVIITFHNEARSTLLRTIVSVLNRSPE 231
            ||..|||.:..:||: ||||.|.|..:|::.  .||.|||||.|||||.||||||:.|||..||.
Human   150 FNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPA 214

  Fly   232 HLIREIVLVDDYS--DHPEDGLE--LAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSH 292
            .|::||:||||.|  ::..|.|:  :.:...|:::|..:|:||:.:|:.||..|.:..|||||:|
Human   215 ILLKEIILVDDASVDEYLHDKLDEYVKQFSIVKIVRQRERKGLITARLLGATVATAETLTFLDAH 279

  Fly   293 VECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQY-----IGASADLRGGFDWNLIFKWEYLS 352
            .||...||||||.|:.|:.|.||.|.|..|.::.|::     .|::.: ||.|||:|.|.||.|
Human   280 CECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHN-RGNFDWSLSFGWESL- 342

  Fly   353 PSERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEI 417
            |.....|..|.|..|:||..|||||.|.|.||..:|.||.:|::|||||:|:|||||||||.|||
Human   343 PDHEKQRRKDETYPIKTPTFAGGLFSISKEYFEYIGSYDEEMEIWGGENIEMSFRVWQCGGQLEI 407

  Fly   418 IPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYY----NAVPLAKNIPFGNID 478
            :|||.||||||.:.|::||.|: .|.|||..|.||||||:||:.:|    :|..:.|...||::.
Human   408 MPCSVVGHVFRSKSPHSFPKGT-QVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKAFGDLS 471

  Fly   479 DRLALKEKLHCKPFKWYLENVYPDLQAPD--P------QEVGQFRQDSTECLDTMGHLIDG--TV 533
            .|..:|.:|.||.|.|||.|:||::..||  |      :.|||     ..||| :|....|  .:
Human   472 KRFEIKHRLQCKNFTWYLNNIYPEVYVPDLNPVISGYIKSVGQ-----PLCLD-VGENNQGGKPL 530

  Fly   534 GIFPCHNTGGNQEWAFTKRGEIKHD---DLCLTLVTFARGSQVVLKACD-------DSENQRWIM 588
            .::.||..||||.:.::.:.||:|:   :|||    .|....|.||||.       .:..|.|.:
Human   531 IMYTCHGLGGNQYFEYSAQHEIRHNIQKELCL----HAAQGLVQLKACTYKGHKTVVTGEQIWEI 591

  Fly   589 REGGLVRHYKINVCLDSRDQSQQGVSAQHCNSALGTQRW 627
            ::..|:.:..:.:||.:..:....||   ||.:...|:|
Human   592 QKDQLLYNPFLKMCLSANGEHPSLVS---CNPSDPLQKW 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	123/240 (51%)
		pp-GalNAc-T	205..500	CDD:133004	152/307 (50%)
		Ricin_B_lectin	511..627	CDD:279046	36/127 (28%)
		RICIN	513..629	CDD:238092	35/127 (28%)
GALNT3	NP_004473.2	Catalytic subdomain A	184..293		56/108 (52%)
		pp-GalNAc-T	188..493	CDD:133004	152/307 (50%)
		Catalytic subdomain B	356..418		41/61 (67%)
		Ricin_B_lectin	506..627	CDD:306998	36/133 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820