Protein Alignment Pgant2 and GALNT1

DIOPT Version :9

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001371367.1
• Gene: GALNT1 / 2589
• HGNCID: 4123
• Length: 559
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 242/533 - (45%)
• Similarity: 319/533 - (59%)
• Gaps: 41/533 - (7%)

  Fly   116 EETSQGLSGGT---------GGPG--GRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNR 169
            |:..:||..|.         .|||  |:..|.|.   .:.|...|...|              |:
Human    36 EKKERGLPAGDVLEPVQKPHEGPGEMGKPVVIPK---EDQEKMKEMFKI--------------NQ 83

  Fly   170 FNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLI 234
            ||..||:.:..||.:||.|...|:||.|.::||.|||:|.|||||.||||||:.||:||||.|:|
Human    84 FNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMI 148

  Fly   235 REIVLVDDYSDHP------EDGLELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHV 293
            .|||||||.|:..      |..::..|: .|.|||.::|.||:|:|:|||..:...|:||||:|.
Human   149 EEIVLVDDASERDFLKRPLESYVKKLKV-PVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHC 212

  Fly   294 ECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAM 358
            ||...||||||.|::.|...||||:|||||.|.|:|:..|....|||:|.|.|:|..:...|...
Human   213 ECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDR 277

  Fly   359 RHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRV 423
            |..|.|..:|||.:|||||.||:.||.::|.||..||:|||||||||||:|||||:|||:.||.|
Human   278 RKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHV 342

  Fly   424 GHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLH 488
            ||||||..|||||||:|.:..:|.||.||||||::|..:|...|....:.:|:|..|:.|:.||.
Human   343 GHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQ 407

  Fly   489 CKPFKWYLENVYPDLQAPDPQ-EVGQFRQ-DSTECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTK 551
            ||||.|||||:|||.|.|... .:|:.|. ::.:|||.|....:..||||.||..||||.:::|.
Human   408 CKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTA 472

  Fly   552 RGEIKHDDLCLTLVTFARGSQVVLKACDDSENQRWIMREGGL-VRHYKINVCLD-SRDQSQQGVS 614
            ..||:.|||||. |:...|...:||......||.|......| ::|...|.||| :.::..|..|
Human   473 NKEIRTDDLCLD-VSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPS 536

  Fly   615 AQHCNSALGTQRW 627
            .:.||.: .:|:|
Human   537 IRDCNGS-RSQQW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	132/237 (56%)
		pp-GalNAc-T	205..500	CDD:133004	164/300 (55%)
		Ricin_B_lectin	511..627	CDD:279046	42/118 (36%)
		RICIN	513..629	CDD:238092	42/118 (36%)
GALNT1	NP_001371367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..65		5/19 (26%)
		Catalytic subdomain A	115..225		61/110 (55%)
		pp-GalNAc-T	119..419	CDD:133004	164/300 (55%)
		Catalytic subdomain B	285..347		42/61 (69%)
		Ricin_B_lectin	432..548	CDD:395527	42/117 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820