DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant2 and Pgant9

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	677	Identity:	263/677 - (38%)
Similarity:	350/677 - (51%)	Gaps:	93/677 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IKLIVFVSIIWMFVMVYYFQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTARQWAPAGGG 69
            :||:.|...||..:                        |...|.||:...||...|   ..:|.|
  Fly    13 VKLVAFALAIWFCI------------------------AFLVYTDDTRRRAAQEGA---GASGAG 50

  Fly    70 AGPGAAAGAAGSGADDP----------------GGNVILIGSVKDFERNA--------------V 104
            :.||...||.|.|  ||                .||||..|..|.....|              .
  Fly    51 SAPGVGGGAGGLG--DPIALALRNEPAGEDFGINGNVIGGGGQKQAHDEADIPPTVGKHKADLQA 113

  Fly   105 HGLKLNGIVALEETSQGLSGGTGGPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNR 169
            ..::.......::..|..|.....|.......|...|..|....|.......|:   :|.:.:|.
  Fly   114 ERMRKKAAEQPKKKPQEDSKKVIDPPANFEENPGELGKPVRLPKEMSDEMKKAV---DDGWTKNA 175

  Fly   170 FNQEASDALPSNRDIPDTRNPMCRTK-KYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHL 233
            |||..||.:..:|.:||.|:..|:.: :|..:||:|.|||.|||||.:.||||:.|||:||||||
  Fly   176 FNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHL 240

  Fly   234 IREIVLVDDYSDHPEDGLEL----AKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVE 294
            |.:|:|||||||.|....:|    |...||::||..|||||:|:|:.||:.|.|.|||:||||.|
  Fly   241 IGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCE 305

  Fly   295 CNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYI-----GASADLRGGFDWNLIFKWEYLSPS 354
            |.|.||||||:|:..:.|.||||||||||.:..:|.     |.:.   |||||||.|.|..:...
  Fly   306 CTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNV---GGFDWNLQFSWHPVPER 367

  Fly   355 ERAMRHNDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIP 419
            || .|||.....:.:|.:|||||.||:.:|::||.||...|:|||||||:||:.|.|||:|||:|
  Fly   368 ER-KRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVP 431

  Fly   420 CSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALK 484
            ||.|||:||||.||.:..|. ||..:|:.|.||||||:|.|:||:.:...|. .:|::.||..|:
  Fly   432 CSHVGHIFRKRSPYKWRSGV-NVLKKNSVRLAEVWMDEYSQYYYHRIGNDKG-DWGDVSDRRKLR 494

  Fly   485 EKLHCKPFKWYLENVYPDLQAP-DPQEVGQFRQ---DSTECLDTMG---HLIDGTVGIFPCHNTG 542
            ..|.||.|||||:|:||:|..| |....|:.|.   ....|||...   |. ...||.:|||..|
  Fly   495 NDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRTCLDAPAGKKHQ-KKAVGTYPCHRQG 558

  Fly   543 GNQEWAFTKRGEIKHDDLCLTLVTFARGSQVVLKACDDSE-NQRWIMREGGLVRHYKIN-VCLDS 605
            |||.|..:|.|||:.||.||...    |..|.|..|...: ||.|..||.....|:..: .|| :
  Fly   559 GNQYWMLSKAGEIRRDDSCLDYA----GKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCL-A 618

  Fly   606 RDQSQQGVSAQHCNSALGTQRWSFGKY 632
            ..:|:..:..:.|:::|..|:|:...|
  Fly   619 ISESKDKLLMEECSASLSRQQWTLENY 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	135/240 (56%)
		pp-GalNAc-T	205..500	CDD:133004	163/303 (54%)
		Ricin_B_lectin	511..627	CDD:279046	40/123 (33%)
		RICIN	513..629	CDD:238092	40/123 (33%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	152/275 (55%)
		pp-GalNAc-T	213..510	CDD:133004	163/302 (54%)
		Ricin_B_lectin	521..640	CDD:279046	40/124 (32%)
		RICIN	523..642	CDD:238092	41/124 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60373at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850