Protein Alignment Pgant2 and gly-3

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_498722.1
• Gene: gly-3 / 176112
• WormBaseID: WBGene00001628
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 258/657 - (39%)
• Similarity: 347/657 - (52%)
• Gaps: 90/657 - (13%)

  Fly     6 KLIVFVSIIWMF----VMVYYFQSST---------EKVENRALRLREVATAMQQYQD-DSSSAAA 56
            :.::..||:|:.    ::.||...||         .::.|||.|:..:..|.|...| |:.....
 Worm    13 RAVIATSIVWLLIDVVILFYYLDPSTSQQQPFPEDNRILNRARRIEPLPPAAQHDSDPDAHPIQP 77

  Fly    57 ASTARQWAPAGGGAGPGAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEETSQG 121
            ....:|..|.                               |.|       ..|.:..|.|| |.
 Worm    78 EKQEKQVYPV-------------------------------DKE-------TANQLRKLMET-QA 103

  Fly   122 LSGGTGGPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPD 186
            ...|..|.||.....|..:.|          |:       |..::.|:||..||:.:..||.:||
 Worm   104 FGPGYHGQGGTGVTVPEDKKT----------IK-------EKRFLENQFNVVASEMISVNRTLPD 151

  Fly   187 TRNPMCRTKKYR---EDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDH-- 246
            .|:..|||....   ..:|:||:||.|||||.:|||||:.||:||||.||:.||:||||.||.
 Worm   152 YRSDACRTSGNNLKTAGMPKTSIIIVFHNEAWTTLLRTLHSVINRSPRHLLEEIILVDDKSDRDY 216

  Fly   247 ---PEDG-LELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERV 307
               |.|. :::..| .:.::..:.|.||:|:|:.|::.|...:|.|||:|||..:.|||||:.||
 Worm   217 LVKPLDSYIKMFPI-PIHLVHLENRSGLIRARLTGSEMAKGKILLFLDAHVEVTDGWLEPLVSRV 280

  Fly   308 REDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMI 372
            .||..|||.|:|||||.|.|:|:.||....|||:|:|.|:|..:...|...|.:|.:..|:||.|
 Worm   281 AEDRKRVVAPIIDVISDDTFEYVTASETTWGGFNWHLNFRWYAVPKRELNRRGSDRSMPIQTPTI 345

  Fly   373 AGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPG 437
            |||||.|||.:|..:|.||..|.||||||||||||||.|||||||.|||||||||||:.||||||
 Worm   346 AGGLFAIDKQFFYDIGSYDEGMQVWGGENLEISFRVWMCGGSLEIHPCSRVGHVFRKQTPYTFPG 410

  Fly   438 GSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPD 502
            |:..|...|..|.||||||:||..:|..||.|:|:..|::.:|..|:|.|.||.|||||||:||:
 Worm   411 GTAKVIHHNAARTAEVWMDEYKAFFYKMVPAARNVEAGDVSERKKLRETLQCKSFKWYLENIYPE 475

  Fly   503 LQAP-DPQEVGQFRQDSTE-CLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHDDLCLTL- 564
            ...| |.:.:|......|| |:||.|.......||..||..||||.|:.|.:|||:.|||||:.
 Worm   476 APLPADFRSLGAIVNRFTEKCVDTNGKKDGQAPGIQACHGAGGNQAWSLTGKGEIRSDDLCLSSG 540

  Fly   565 VTFARGSQVVLKACDDSE-NQRWIM---REGGLVRHYKINVCLDSRDQSQQGVSAQHCNSALGTQ 625
            ..:..||::.|:.|..|: |.:.:.   .:.|.:.|.|...|:...||.   |:...|......|
 Worm   541 HVYQIGSELKLERCSVSKINVKHVFVFDDQAGTLLHKKTGKCVTGADQR---VTLDECGLGRKDQ 602

  Fly   626 RWSFGKY 632
            .|....|
 Worm   603 MWQLEGY 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	165/300 (55%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	41/124 (33%)
gly-3	NP_498722.1	pp-GalNAc-T	173..473	CDD:133004	165/300 (55%)
		beta-trefoil_Ricin_GALNT1-like	481..608	CDD:467311	42/129 (33%)