DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant2 and gly-6

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001022644.1	Gene:	gly-6 / 175558	WormBaseID:	WBGene00001631	Length:	618	Species:	Caenorhabditis elegans

Alignment Length:	492	Identity:	210/492 - (42%)
Similarity:	295/492 - (59%)	Gaps:	38/492 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 NRFNQEASDALPSNRDIPDTRNPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEH 232
            |:||...||.:...|.:|:.|.|.||...|.::||.|||||.:||||.||||||:.||::|||:.
Worm   123 NQFNLLVSDGISVRRSLPEIRKPSCRNMTYPDNLPTTSVIIVYHNEAYSTLLRTVWSVIDRSPKE 187

  Fly   233 LIREIVLVDDYSDHPEDGLELAKID--------KVRVIRNDKREGLVRSRVKGADAAVSSVLTFL 289
            |::||:||||:||  .:.|....:|        .:::||:.:|.||:|:|:.||..|...|||||
Worm   188 LLKEIILVDDFSD--REFLRYPTLDTTLKPLPTDIKIIRSKERVGLIRARMMGAQEAQGDVLTFL 250

  Fly   290 DSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPS 354
            |||.||.:.||||||.|::.:...|.|||||:|:.:.|||.......||||:|||.|:| |..|:
Worm   251 DSHCECTKGWLEPLLTRIKLNRKAVPCPVIDIINDNTFQYQKGIEMFRGGFNWNLQFRW-YGMPT 314

  Fly   355 ERAMRH-NDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEII 418
            ..|.:| .|||..|.:|.:|||||.|::.||.:||:||..||:|||||||:|||:|||||.:||:
Worm   315 AMAKQHLLDPTGPIESPTMAGGLFSINRNYFEELGEYDPGMDIWGGENLEMSFRIWQCGGRVEIL 379

  Fly   419 PCSRVGHVFRKRHPYTFPG-GSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFG-NIDDRL 481
            |||.|||||||..|:.||| .||.|...|..|.|||||||:|.::|...|.|..:... ::.:|:
Worm   380 PCSHVGHVFRKSSPHDFPGKSSGKVLNTNLLRVAEVWMDDWKHYFYKIAPQAHRMRSSIDVSERV 444

  Fly   482 ALKEKLHCKPFKWYLENVYPDLQAPDP-QEVGQF--RQDSTECLD-TMGHLIDGTVGIFPC---- 538
            .|::||:||.|||||:||:.|...|.| ...|:.  ..:|:.||. |:......|.....|
Worm   445 ELRKKLNCKSFKWYLQNVFQDHFLPTPLDRFGRMTSSSNSSVCLAWTLRSSGIKTASTADCLKIF 509

  Fly   539 HNTGGNQEWAFTKRGEIKHDD-LCLTLVTFARGS---QVVLKACDDSENQRWIMR-EGGLVRHYK 598
            |.|   |.|.:|....|:.|: |||::|.....:   ::.||.|...:.:.|..: :.|..::.|
Worm   510 HKT---QLWLYTGDRRIRTDEHLCLSVVQLLHTTSDWKIQLKECAGFDTEYWDFKPKIGRFQNRK 571

  Fly   599 INVCLDS-------RDQSQQGVSAQHCNSALGTQRWS 628
            ..:||.|       :|:....: .|.|.|:...|.|:
Worm   572 TGLCLASPDIFDPTKDEFNPPI-VQKCRSSNDRQNWT 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	129/240 (54%)
		pp-GalNAc-T	205..500	CDD:133004	158/305 (52%)
		Ricin_B_lectin	511..627	CDD:279046	32/134 (24%)
		RICIN	513..629	CDD:238092	32/135 (24%)
gly-6	NP_001022644.1	WcaA	155..451	CDD:223539	152/298 (51%)
		pp-GalNAc-T	160..463	CDD:133004	158/305 (52%)
		Ricin_B_lectin	474..606	CDD:279046	32/135 (24%)
		RICIN	476..608	CDD:238092	33/136 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920