DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Galnt10

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_038941033.1	Gene:	Galnt10 / 170501	RGDID:	69409	Length:	752	Species:	Rattus norvegicus

Alignment Length:	531	Identity:	206/531 - (38%)
Similarity:	288/531 - (54%)	Gaps:	55/531 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 GTGGPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRN 189
            |.|..|...|:      |:.|..::|              |..|.||...||.:..||.:||.|:
  Rat   237 GNGEQGKPYPM------TDAERVDQA--------------YRENGFNIYVSDKISLNRSLPDIRH 281

  Fly   190 PMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSD--HPEDGLE 252
            |.|.:|.|.|.||.||:||.||||..|:||||:.|||||||..|:.|||||||:||  |.:..||
  Rat   282 PNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLE 346

  Fly   253 --LAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVV 315
              :|....||::|..|||||:|:|:.||.||...|:||||||.|.|..||.|||:|:..:...:|
  Rat   347 DYMALFPSVRILRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIV 411

  Fly   316 CPVIDVISMDNFQYIGASAD-LRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVI 379
            ||:||||..|:|:|...:.| :||.|||.:.:|...:.|.   ::..||:....:|::|||||.:
  Rat   412 CPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPE---LQKADPSDPFESPVMAGGLFAV 473

  Fly   380 DKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFA 444
            |:.:|.:||.||..:::||||..||||:||.|||.:|.||||||||::||..||..|.|..  .|
  Rat   474 DRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVS--LA 536

  Fly   445 RNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENV-------YPD 502
            ||.:|.||||||:|.::.|...|..:::..|::..:..|:..|:||.|||::..:       ||.
  Rat   537 RNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFYPP 601

  Fly   503 LQAPDPQEVGQFRQDSTE-CLDTMGHLIDGTVGIFPCHNTGGNQEW------AFTKRGEIKHDD- 559
            :: |.....|:.|...|. |.||....:...:.:..|....|...|      .||.|.:|:..|
  Rat   602 VE-PPAAAWGEIRNVGTGLCTDTKHGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDP 665

  Fly   560 -----LCLTLVTFARGSQVVLKACDDSE-NQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQHC 618
                 .|...|:..  |.|.|..|...: ||.|..|:...:.|.....|:|. .:|...:....|
  Rat   666 QHTKKFCFDAVSHT--SPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC-SESDHRIFMNTC 727

  Fly   619 NSALGTQRWSF 629
            |.:..||:|.|
  Rat   728 NPSSLTQQWLF 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	121/236 (51%)
		pp-GalNAc-T	205..500	CDD:133004	143/306 (47%)
		Ricin_B_lectin	511..627	CDD:279046	32/129 (25%)
		RICIN	513..629	CDD:238092	32/129 (25%)
Galnt10	XP_038941033.1	pp-GalNAc-T	297..592	CDD:133004	143/299 (48%)
Galnt10	XP_038941033.1	Ricin_B_lectin	608..736	CDD:395527	32/130 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810