DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and GALNTL5

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_016867282.1	Gene:	GALNTL5 / 168391	HGNCID:	21725	Length:	496	Species:	Homo sapiens

Alignment Length:	383	Identity:	165/383 - (43%)
Similarity:	230/383 - (60%)	Gaps:	35/383 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 APSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYRED 200
            |.|..||:..:.|..  :....|:.|        ||...|.:|...|::||||:.||..|.|...
Human   131 AKSMLGTDFNHTNPE--LHKELLKYG--------FNVIISRSLGIEREVPDTRSKMCLQKHYPAR 185

  Fly   201 LPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKID-------- 257
            ||..|::|.|:||..:.|.:|:.||.|.:|.:.:.||:||||.|  ..|.|: .|:|
Human   186 LPTASIVICFYNEECNALFQTMSSVTNLTPHYFLEEIILVDDMS--KVDDLK-EKLDYHLETFRG 247

  Fly   258 KVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVI 322
            ||::|||.|||||:|:|:.||..|...||.|||||.|.|.:||||||..:.:||..||||:||||
Human   248 KVKIIRNKKREGLIRARLIGASHASGDVLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVI 312

  Fly   323 SMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDP---TTAIRTPMIAGGLFVIDKAYF 384
            .....:| ..|..:||.|||||.|||:.:...|.    :.|   |..||:|.::||:|.|.:.||
Human   313 DDRTLEY-KPSPLVRGTFDWNLQFKWDNVFSYEM----DGPEGSTKPIRSPAMSGGIFAIRRHYF 372

  Fly   385 NKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKR--HPYTFPGGSGNVFARNT 447
            |::|:||..||.||.||||:|.|:|.|||.|.|||||||||:.:|:  .|.|..    :....|.
Human   373 NEIGQYDKDMDFWGRENLELSLRIWMCGGQLFIIPCSRVGHISKKQTGKPSTII----SAMTHNY 433

  Fly   448 RRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQA 505
            .|...||:|:||:.::...|..|.:.:|||.:|:.|:::|.||.|:|||:||:|:|:|
Human   434 LRLVHVWLDEYKEQFFLRKPGLKYVTYGNIRERVELRKRLGCKSFQWYLDNVFPELEA 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	117/244 (48%)
		pp-GalNAc-T	205..500	CDD:133004	139/307 (45%)
		Ricin_B_lectin	511..627	CDD:279046
		RICIN	513..629	CDD:238092
GALNTL5	XP_016867282.1	GT2	187..437	CDD:224137	120/261 (46%)
GALNTL5	XP_016867282.1	pp-GalNAc-T	190..486	CDD:133004	139/307 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820