Protein Alignment Pgant2 and Galnt4

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_056552.1
• Gene: Galnt4 / 14426
• MGIID: 894692
• Length: 578
• Species: Mus musculus
• Alignment Length: 519
• Identity: 228/519 - (43%)
• Similarity: 304/519 - (58%)
• Gaps: 44/519 - (8%)

  Fly   139 GRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYR-EDLP 202
            ||.:::: .||      |.|:..|:...|...|...||.:..:|.|.|.|...|:.||:. ..||
Mouse    78 GRASKLQ-LNE------GELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKAKKFHYRSLP 135

  Fly   203 ETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSD--HPEDGLE--LAKIDKVRVIR 263
            .|||||.|:|||.|||||||.|||..||..|::||:||||.||  :.:..||  ::.:::||:||
Mouse   136 TTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRIYLKAQLETYISNLERVRLIR 200

  Fly   264 NDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQ 328
            .:|||||||:|:.||..|...||||||.|.|||..||||||||:..|.|.:||||||.|..:.|:
Mouse   201 TNKREGLVRARLIGATFATGDVLTFLDCHCECNTGWLEPLLERISRDETAIVCPVIDTIDWNTFE 265

  Fly   329 -YIGASADLRGGFDWNLIFKWEYLSPSERAMRHN--DPTTAIRTPMIAGGLFVIDKAYFNKLGKY 390
             |:.....:.|||||.|.|:|..:...||..|.:  ||   ||:|.:|||||.:.|.||..||.|
Mouse   266 FYMQTGEPMIGGFDWRLTFQWHSVPKHERDRRTSRIDP---IRSPTMAGGLFAVSKKYFQYLGTY 327

  Fly   391 DMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNTRRAAEVWM 455
            |..|:||||||||:|||||||||.|||.|||.|||||.||.||..|.     |.:||.|||||||
Mouse   328 DTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPYARPN-----FLQNTARAAEVWM 387

  Fly   456 DDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPD--PQEVGQFRQ-- 516
            |:||:|:||..|.|:...:|::.:|..|:|:|.||.|.|||:||:.:|..|:  |...|..|.
Mouse   388 DEYKEHFYNRNPPARKEAYGDLSERKLLRERLKCKSFDWYLKNVFSNLHVPEDRPGWHGAIRSMG 452

  Fly   517 DSTECLD---TMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHD---DLCLTLVTFARGSQVVL 575
            .|:||||   ...:.....:.:|.||..||||.:.:|...||:.:   :||..:.  .:...|.:
Mouse   453 ISSECLDYNAPDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVP--QQKDYVGM 515

  Fly   576 KACDDS-----ENQRWIMREGGLVRHYKINVCLDSRDQSQQGVSAQH---CNSALGTQRWSFGK 631
            :.|...     .|..|..:|.|.:.|....:|| |..::.:|..:.|   |::....|.|.|.|
Mouse   516 QNCPKDGLPVPVNIIWHFKEDGTIFHPHTRLCL-SAYRTAEGRPSVHMKTCDALDKNQLWRFEK 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	167/301 (55%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	34/134 (25%)
Galnt4	NP_056552.1	Catalytic subdomain A	134..243		65/108 (60%)
		pp-GalNAc-T	138..432	CDD:133004	167/301 (55%)
		Catalytic subdomain B	303..365		44/64 (69%)
		beta-trefoil_Ricin-like	442..577	CDD:483949	35/137 (26%)