Protein Alignment Pgant2 and Pgant7

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_311182.4
• Gene: Pgant7 / 1272432
• VectorBaseID: AGAMI1_002898
• Length: 598
• Species: Anopheles gambiae
• Alignment Length: 668
• Identity: 222/668 - (33%)
• Similarity: 321/668 - (48%)
• Gaps: 127/668 - (19%)

  Fly     3 RNIKLIVFVSIIWMFVMVYYFQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTARQWAPAG 67
            |..::.|.::|:   :|:.|..::...|::..::                   .|..||..|..|
Mosquito    10 RIFRIAVSLAIV---IMILYMIATWSGVDHHTVK-------------------DAYNARLAAMRG 52

  Fly    68 GGAGPGAAAGAAGSGADD---PGGNVILIGSVKDFE---RNAVHGLKLNGIVALEETSQGLSGGT 126
            .|       |..|:|..|   |.....|:..:.:||   :..|.|                 .|.
Mosquito    53 HG-------GDVGNGEQDRNHPKEVPQLVEGLGNFEPADKPMVDG-----------------PGE 93

  Fly   127 GGPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPM 191
            ||....||.....|.|:.|.  |.|                  .|...|||:..:|.|.|||...
Mosquito    94 GGKAYVLPEDQQNRATDAEM--EYG------------------MNIVVSDAISLDRTIKDTRLEE 138

  Fly   192 CRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPE-------- 248
            |:...|...||.|||:|.||||..|.|:||:.|||||||:||:.||:|||||||..:
Mosquito   139 CKHWDYPYHLPRTSVVIVFHNEGFSVLMRTVHSVLNRSPKHLLHEIILVDDYSDKEDLKGKLERY 203

  Fly   249 ----DGLELAKIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVRE 309
                ||:       ||:|||.:||||:|:|.:||..|...|:.:||:|.|.|..||.|||..:..
Mosquito   204 IERFDGM-------VRLIRNSEREGLIRTRSRGAKEATGEVIVYLDAHCEVNTNWLPPLLAPIHR 261

  Fly   310 DPTRVVCPVIDVISMDNFQYIGASAD---LRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPM 371
            |.|.:..|:||.|....|:|....||   .||.|:|.:::|...:...|:..|.:| :...|:|.
Mosquito   262 DRTVMTVPIIDGIDHKTFEYRPVYADGHHYRGIFEWGMLYKENEVPRREQKRRKHD-SEPYRSPT 325

  Fly   372 IAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFP 436
            .|||||.|::.:|.:||.||..:.||||||.|:||::||||||:|.:||||||||:|...||.|
Mosquito   326 HAGGLFAINRKFFLELGAYDSGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNF- 389

  Fly   437 GG------SGNVFARNTRRAAEVWMD-DYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKW 494
             |      .|.:...|.:|..|.|.| .||:::|...|||:.:..|:|.::|||||:|.||.|:|
Mosquito   390 -GKLANKKKGPLITINYKRVIETWFDGPYKEYFYTREPLARFLDMGDISEQLALKERLQCKSFQW 453

  Fly   495 YLENV-------YPDLQA----PDPQEVGQFRQDSTECLDTMGHLIDGTVGIFPCHNTGGNQEWA 548
            |::||       ||.|.|    .:.|.||:     .:|:|.:|......:|:..||..|.||...
Mosquito   454 YMDNVAYDVLDKYPMLPANVKWGELQNVGK-----EKCVDALGRQPPAVIGLQQCHGQGHNQLIR 513

  Fly   549 FTKRGEIKHDDLCLTLVTFARGSQVVLKACD-DSENQRWIMRE-GGLVRHYKINVCLDSRDQSQQ 611
            ....|::...:.|:.    |..|::.|..|. .:.:..|...| .|.:.|.....|:..:.|::|
Mosquito   514 LNGAGQLGVGERCIE----AYNSEIKLAFCRLGTVDGPWQYDEQSGTLLHRTHKKCMGYQPQTRQ 574

  Fly   612 GVSAQHCNSALGTQRWSF 629
             ::...|:.....|.|.|
Mosquito   575 -LALMPCDINNAYQSWKF 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	143/323 (44%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	27/120 (23%)
Pgant7	XP_311182.4	pp-GalNAc-T	152..459	CDD:133004	142/316 (45%)
		beta-trefoil_Ricin_GALNT7	471..593	CDD:467315	30/131 (23%)