Protein Alignment Pgant2 and Pgant1

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_308833.5
• Gene: Pgant1 / 1270158
• VectorBaseID: AGAMI1_002243
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 669
• Identity: 246/669 - (36%)
• Similarity: 341/669 - (50%)
• Gaps: 98/669 - (14%)

  Fly     1 MRRNI-KLIVFVSIIWMFVMVYY--FQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTARQ 62
            :|||: ..::.:.::.:||:.|:  ...|...:.:.||   |.|..:.|...|.:.....:.|.
Mosquito     9 IRRNLYTRVLLLLVLGLFVLFYFKNLNGSPNSLGSPAL---EQAKPLAQLGLDVNRLELLAAAE- 69

  Fly    63 WAPAGGGAGPGAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEETSQGLSGGTG 127
             |.|||....|....|.     .|.|:.:       |||          :|..:...|....|..
Mosquito    70 -AAAGGPLNKGNLLPAL-----PPSGDAL-------FER----------LVLADLAKQRPGLGNN 111

  Fly   128 GPGGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMC 192
            |.|..|    :|...|:                ||........|:|.|:.|..||..||.|:|.|
Mosquito   112 GEGVEL----TGDAKEI----------------GEKQLATIALNEELSEHLSYNRTPPDGRHPAC 156

  Fly   193 RTKKY-REDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLEL-AK 255
            :.|.| ...||.|:|||.|:||..|.||||:.||||.:...|:|||:||||.|.:    :|| .|
Mosquito   157 KRKHYDLTGLPSTNVIIIFYNEPYSVLLRTVHSVLNTADGRLLREIILVDDGSTN----VELKGK 217

  Fly   256 ID---------KVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDP 311
            :|         ||:|:|..:|.||:|:|:.||..|.:.||.|||:|.||...||||||||::|.|
Mosquito   218 LDYYVRTRLPAKVKVLRQRQRVGLIRARLAGARLAKADVLVFLDAHCECMVQWLEPLLERIKESP 282

  Fly   312 TRVVCPVIDVISMDNFQYIGASADLR----GGFDWNLIFKWEYLSPSERAMRHND---------P 363
            |.|:.|:||||...||.|  ::.|..    |||.|:..|.|..::..||..:..:         |
Mosquito   283 TSVLVPIIDVIEAKNFYY--STNDYNDFQIGGFTWDGHFDWHDVTKRERERQKRECAEKDLEICP 345

  Fly   364 TTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFR 428
            |   .:|.:|||||.|.:.||..:|.||.:||.|||||||:|||||||||:||.|||||:||:||
Mosquito   346 T---YSPTMAGGLFAIARDYFWDIGSYDEQMDGWGGENLEMSFRVWQCGGTLETIPCSRIGHIFR 407

  Fly   429 KRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNIP-FGNIDDRLALKEKLHCKPF 492
            ..|||:|| .:.:....||.|.|.||||||.:..|...|..|:.| .|::..|..|:||||||.|
Mosquito   408 DFHPYSFP-NNRDTHGINTVRMAIVWMDDYVELLYLNRPDLKDHPELGDVTHRKVLREKLHCKSF 471

  Fly   493 KWYLENVYPDLQAPDPQEVGQF----RQDSTECLDTMGHLID--GTVGIFPCH--NTGGNQEWAF 549
            .||::||||:...| .:.|..|    .|....||||:....|  ..:||:.|.  ....:|.::.
Mosquito   472 DWYMKNVYPEKFIP-TRNVRAFGRLASQADNLCLDTLQQNADKPWNLGIYTCFKPEVSASQLFSL 535

  Fly   550 TKRGEIKHDDLCLTLVTFARGSQ-VVLKACDDSE--NQRWIMREGGLVRHYKINVCLDSRDQSQQ 611
            |||..::::..|.|:......|: ||:..|.|.|  :..|...|...:||.:..:||||.|.|.:
Mosquito   536 TKRNVLRNERSCATVQASKSESKFVVMIPCIDDEDIDDTWEFTEHRQLRHKQSGLCLDSSDLSTK 600

  Fly   612 G-VSAQHCNSALGTQRWSF 629
            . |....|:..:.||:|.|
Mosquito   601 SYVHVATCHPGIKTQKWEF 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	152/318 (48%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	38/130 (29%)
Pgant1	XP_308833.5	None