Protein Alignment Pgant2 and galnt6

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_002933739.1
• Gene: galnt6 / 100497888
• XenbaseID: XB-GENE-983702
• Length: 622
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 240/613 - (39%)
• Similarity: 329/613 - (53%)
• Gaps: 84/613 - (13%)

  Fly    79 AGSGA-DDPGGNVILI--GSVKDFERNAVHGLK-----LNGIVALEETSQGLSGGTGGP------ 129
            ||:|| |||....|::  ..:.|..|.|::.|.     |..:..::|.         ||
 Frog    31 AGNGAKDDPWIKNIVVRKDQMLDMMRGAMNNLNDFIPDLQIMAPVQEE---------GPVEEKKS 86

  Fly   130 --------------GGRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPS 180
                          ..|.|..|:..|.:.:.|.:..:... ..:..|..:.::.||..|||.:..
 Frog    87 CLPEYYTPAELKPFMERPPQDPNSPGADGKEFKKDTWTEE-ETKEKEKGFDKHHFNAFASDRISL 150

  Fly   181 NRDI-PDTRNPMCRTKKYRE--DLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDD 242
            :|.: ||||.|:|..:|::.  .||.|||||.|||||.||||||:.|||..||..|::||:||||
 Frog   151 HRALGPDTRPPVCIEQKFKRCPSLPTTSVIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDD 215

  Fly   243 YSDHPEDGLELAKIDK-------VRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWL 300
            .|   ||.....|:|.       |::.|..:|:||..:|:.||..|...||||||:|.||...||
 Frog   216 AS---EDEYLKEKLDDYVKALQIVKIARQKERKGLTTARLLGASIATGEVLTFLDAHCECFHGWL 277

  Fly   301 EPLLERVREDPTRVVCPVIDVISMDNFQY-----IGASADLRGGFDWNLIFKWEYLSPSERAMRH 360
            ||||.|:.||.|.||.|.|.:|.:::|::     .|.:.: ||.|||:|.|.||.:..:|:. |.
 Frog   278 EPLLSRIAEDHTAVVSPDIPIIDLNSFEFHKPVQYGKTHN-RGNFDWSLTFGWEAIPAAEKE-RR 340

  Fly   361 NDPTTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGH 425
            .|.|..|:||..|||||.|.||||..:|.||.:|::|||||||:|||||||||.|||||||.|||
 Frog   341 KDETYPIKTPTFAGGLFSISKAYFEHIGSYDEEMEIWGGENLEMSFRVWQCGGQLEIIPCSVVGH 405

  Fly   426 VFRKRHPYTFPGGSGNVFARNTRRAAEVWMDDYKQHYY----NAVPLAKNIPFGNIDDRLALKEK 486
            |||.:.|:|||.|:..:| ||..|.|||||||||..||    .|..:.:...||:|..||.||..
 Frog   406 VFRTKSPHTFPKGTQVIF-RNLVRLAEVWMDDYKLLYYQRNEQAAKMVREKSFGDISKRLKLKAD 469

  Fly   487 LHCKPFKWYLENVYPDLQAP--DPQEVGQFRQD-STECLDTMGHLIDGTVGIFP--CHNTGGNQE 546
            |.||.|.|||||:||::..|  ||...|:.:.: |..|||. |....|...:..  |:..||.|.
 Frog   470 LQCKNFTWYLENIYPEMFVPDRDPTYYGKVKNEGSQNCLDA-GEKNHGGKPLIMNLCNGMGGTQY 533

  Fly   547 WAFTKRGEIKHD---DLCLTLVTFARGSQVVLKACDDS-------ENQRWIMREGGLVRHYKINV 601
            :.::...|::|:   .|||. ..:..| .|.|..|...       .|:.|.:.:..|:::...|:
 Frog   534 FEYSTHKELRHNIAKQLCLR-SKYVPG-PVELGECQYKGKRTTVPGNEEWELTKDRLLKNVGSNM 596

  Fly   602 CLDSRDQSQQGVSAQHCNSALGTQRWSF 629
            ||.:|.::.   |...||.:...|||.|
 Frog   597 CLTARGENP---STAECNPSDIHQRWGF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	163/310 (53%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	33/131 (25%)
galnt6	XP_002933739.1	pp-GalNAc-T	178..483	CDD:133004	163/310 (53%)
		beta-trefoil_Ricin-like	493..622	CDD:483949	35/135 (26%)