DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and Galnt6

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001165534.1	Gene:	Galnt6 / 100361647	RGDID:	2319726	Length:	622	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	229/536 - (42%)
Similarity:	316/536 - (58%)	Gaps:	57/536 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 RLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDI-PDTRNPMCRTK 195
            |.|..|:..|.:.:.|.:..:... ..:..::.|.::.||..|||.:...|.: ||||.|.|..:
  Rat   105 RPPQDPNSPGADGKAFQKKEWTLL-ETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQ 168

  Fly   196 KYRE--DLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYS--DHPEDGLE--LA 254
            |:|.  .||.|||:|.|||||.||||||:.|||:.||..|::||:||||.|  :|.::.||  :.
  Rat   169 KFRRCPPLPTTSVVIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKLERYVQ 233

  Fly   255 KIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVI 319
            ::..|||:|..:|:||:.:|:.||..|.:.||||||:|.||...||||||.|:.||.|.||.|.|
  Rat   234 QLQIVRVVRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDI 298

  Fly   320 DVISMDNFQYI----GASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVID 380
            ..|.::.||:.    ...|..||.|||:|.|.||.| |.....|..|.|..|::|..|||||.|.
  Rat   299 VTIDLNTFQFSKPMRRGKAHSRGNFDWSLTFGWEML-PEHEKQRRKDETYPIKSPTFAGGLFSIS 362

  Fly   381 KAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFAR 445
            ||||..:|.||.:|::|||||:|:|||||||||.|||||||.||||||.:.|:|||.|: :|.||
  Rat   363 KAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGT-SVIAR 426

  Fly   446 NTRRAAEVWMDDYKQHYY----NAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAP 506
            |..|.|||||||||:.:|    .|..:||...||::.:||.|:|:|||..|.|||.||||::..|
  Rat   427 NQVRLAEVWMDDYKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYLHNVYPEMFVP 491

  Fly   507 D--PQEVGQFRQ-DSTECLDTMGHLIDGTVG----------IFPCHNTGGNQEWAFTKRGEIKHD 558
            |  |...|..:. .:::|||         ||          ::.|||.||||.:.:|.:.:::|:
  Rat   492 DLNPTFSGAIKNLGTSQCLD---------VGENNRGGKPLIMYVCHNLGGNQYFEYTSQRDLRHN 547

  Fly   559 ---DLCLTLVTFARGSQVVLKACD----DSE---NQRWIMREGGLVRHYKINVCLDSRDQSQQGV 613
               .|||    .|.||.:.|:.|.    :||   ::.|.:.:..|:|:.....||.|:|:..
  Rat   548 IGKQLCL----HASGSTLGLRNCQFIGKNSEVPKDEEWELTQDQLIRNLGSGTCLTSKDKKP--- 605

  Fly   614 SAQHCNSALGTQRWSF 629
            :...||.:...|.|.|
  Rat   606 AMAPCNPSDPYQLWLF 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	129/239 (54%)
		pp-GalNAc-T	205..500	CDD:133004	163/306 (53%)
		Ricin_B_lectin	511..627	CDD:279046	35/136 (26%)
		RICIN	513..629	CDD:238092	35/136 (26%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	163/306 (53%)
Galnt6	NP_001165534.1	Ricin_B_lectin	497..619	CDD:395527	35/137 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920