Protein Alignment Pgant2 and Galnt6

DIOPT Version :10

• Sequence 1: NP_608773.2
• Gene: Pgant2 / 33556
• FlyBaseID: FBgn0031530
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001165534.1
• Gene: Galnt6 / 100361647
• RGDID: 2319726
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 229/536 - (42%)
• Similarity: 316/536 - (58%)
• Gaps: 57/536 - (10%)

  Fly   132 RLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDI-PDTRNPMCRTK 195
            |.|..|:..|.:.:.|.:..:... ..:..::.|.::.||..|||.:...|.: ||||.|.|..:
  Rat   105 RPPQDPNSPGADGKAFQKKEWTLL-ETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQ 168

  Fly   196 KYRE--DLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYS--DHPEDGLE--LA 254
            |:|.  .||.|||:|.|||||.||||||:.|||:.||..|::||:||||.|  :|.::.||  :.
  Rat   169 KFRRCPPLPTTSVVIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKLERYVQ 233

  Fly   255 KIDKVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVI 319
            ::..|||:|..:|:||:.:|:.||..|.:.||||||:|.||...||||||.|:.||.|.||.|.|
  Rat   234 QLQIVRVVRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDI 298

  Fly   320 DVISMDNFQYI----GASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFVID 380
            ..|.::.||:.    ...|..||.|||:|.|.||.| |.....|..|.|..|::|..|||||.|.
  Rat   299 VTIDLNTFQFSKPMRRGKAHSRGNFDWSLTFGWEML-PEHEKQRRKDETYPIKSPTFAGGLFSIS 362

  Fly   381 KAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFAR 445
            ||||..:|.||.:|::|||||:|:|||||||||.|||||||.||||||.:.|:|||.|: :|.||
  Rat   363 KAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGT-SVIAR 426

  Fly   446 NTRRAAEVWMDDYKQHYY----NAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAP 506
            |..|.|||||||||:.:|    .|..:||...||::.:||.|:|:|||..|.|||.||||::..|
  Rat   427 NQVRLAEVWMDDYKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYLHNVYPEMFVP 491

  Fly   507 D--PQEVGQFRQ-DSTECLDTMGHLIDGTVG----------IFPCHNTGGNQEWAFTKRGEIKHD 558
            |  |...|..:. .:::|||         ||          ::.|||.||||.:.:|.:.:::|:
  Rat   492 DLNPTFSGAIKNLGTSQCLD---------VGENNRGGKPLIMYVCHNLGGNQYFEYTSQRDLRHN 547

  Fly   559 ---DLCLTLVTFARGSQVVLKACD----DSE---NQRWIMREGGLVRHYKINVCLDSRDQSQQGV 613
               .|||    .|.||.:.|:.|.    :||   ::.|.:.:..|:|:.....||.|:|:..
  Rat   548 IGKQLCL----HASGSTLGLRNCQFIGKNSEVPKDEEWELTQDQLIRNLGSGTCLTSKDKKP--- 605

  Fly   614 SAQHCNSALGTQRWSF 629
            :...||.:...|.|.|
  Rat   606 AMAPCNPSDPYQLWLF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	pp-GalNAc-T	205..500	CDD:133004	163/306 (53%)
		beta-trefoil_Ricin_GALNT2	510..629	CDD:467312	36/139 (26%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	163/306 (53%)
		beta-trefoil_Ricin-like	495..622	CDD:483949	38/143 (27%)