DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt13

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_005168002.1	Gene:	galnt13 / 100330695	ZFINID:	ZDB-GENE-091204-444	Length:	581	Species:	Danio rerio

Alignment Length:	656	Identity:	248/656 - (37%)
Similarity:	331/656 - (50%)	Gaps:	162/656 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRRNI--KLIVFVSIIWMFVMVY---YFQSSTEKVENRALRLREVATAMQQYQDDSSSAAAASTA 60
            |||.:  |:::..|::|:.|.|:   || |...|.:||
Zfish     1 MRRFVYCKVVLTTSLVWVLVDVFLLLYF-SECNKCDNR--------------------------- 37

  Fly    61 RQWAPAGGGAGPGAAAGAAGSGADDPGGNVILIGSVKDFERNAVHGLKLNGIVALEETSQGLSGG 125
                                                ||      |.|    :.||...   :|..
Zfish    38 ------------------------------------KD------HSL----LPALRAV---MSRA 53

  Fly   126 TGGPG--GRLPVAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTR 188
            ...||  |:..|.|.   .|.:...|...|              |:||..|||.:..||.:||.|
Zfish    54 HEAPGEMGKAVVIPK---EEQDKMKELFKI--------------NQFNLMASDMIALNRSLPDVR 101

  Fly   189 NPMCRTKKYREDLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYS--DHPEDGL 251
            ...|:||.|.:|||.||::|.|||||.||||||:.|.:||||..|:.||:||||.|  |..::.|
Zfish   102 LDGCKTKTYPDDLPNTSIVIVFHNEAWSTLLRTVHSAINRSPRQLLYEILLVDDASERDFLKEKL 166

  Fly   252 E--LAKID-KVRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTR 313
            |  :|.:: .||::|.::|.||:|:|::||.|....|:||||:|.||...|||||:.|::||...
Zfish   167 EDYVATLEVPVRILRMEQRTGLIRARLRGAAATRGQVITFLDAHCECTTGWLEPLMARIKEDRRA 231

  Fly   314 VVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEYLSPSERAMRHNDPTTAIRTPMIAGGLFV 378
            ||||:|||||.:.|:|:..|....|||:|.|.|:|..:...|...|..|.|..:|||.:|||||.
Zfish   232 VVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFS 296

  Fly   379 IDKAYFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVF 443
            ||:.||.::|.||..||:|||||||:|||:|||||||||:.||.|||||||..||:||||:|.|.
Zfish   297 IDRTYFEEIGTYDSGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVI 361

  Fly   444 ARNTRRAAEVWMDDYKQHYYNAVPLAKNIPFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDP 508
            .:|.||.||||||::|..:|...|....:.:|::..|.||:|.|.||||.|||||||||.|.|..
Zfish   362 NKNNRRLAEVWMDEFKDFFYIISPGVVRVDYGDVSSRKALRESLKCKPFSWYLENVYPDSQIPRR 426

  Fly   509 -QEVGQFRQ-DSTECLDTMGHLIDGTVGIFPCHNTGGNQEWAFTKRGEIKHDDLCLTLVTFARGS 571
             ..:|:.|. ::.:|:|.||...:..||.|.||..||||.:::|...||:.|||||. .:...|.
Zfish   427 YYSLGEIRNVETNQCVDNMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTDDLCLD-ASRLNGP 490

  Fly   572 QVVLKA-----------------------------------------------------CDDSEN 583
            .|:||.                                                     ||||..
Zfish   491 VVMLKCHHMKGNQMFEYDAEYVGKWEYDFKKRTFLHIITQSCLTISRLEDGTYGPTVEYCDDSPL 555

  Fly   584 QRWIMR 589
            |.|.:|
Zfish   556 QAWTLR 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	129/236 (55%)
		pp-GalNAc-T	205..500	CDD:133004	160/299 (54%)
		Ricin_B_lectin	511..627	CDD:279046	34/133 (26%)
		RICIN	513..629	CDD:238092	33/131 (25%)
galnt13	XP_005168002.1	Glyco_tranf_2_3	115..359	CDD:290369	133/243 (55%)
		pp-GalNAc-T	118..418	CDD:133004	160/299 (54%)
		RICIN	431..560	CDD:238092	33/129 (26%)
		Ricin_B_lectin	431..558	CDD:279046	32/127 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920