DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant2 and galnt18b

DIOPT Version :9

Sequence 1:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_003199061.1	Gene:	galnt18b / 100310831	ZFINID:	ZDB-GENE-091014-1	Length:	609	Species:	Danio rerio

Alignment Length:	533	Identity:	191/533 - (35%)
Similarity:	284/533 - (53%)	Gaps:	79/533 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 VAPSGRGTEVEYFNEAGYIRAGALRNGEDPYIRNRFNQEASDALPSNRDIPDTRNPMCRTKKYRE 199
            :.|..|...::.|...||       ||   |:        ||.|..:|.|||.|...|:...|..
Zfish   107 LGPESRRVALKMFQYYGY-------NG---YL--------SDRLSMDRAIPDYRPDGCKNMSYPS 153

  Fly   200 DLPETSVIITFHNEARSTLLRTIVSVLNRSPEHLIREIVLVDDYSDHPEDGLELAKIDK------ 258
            :||:.|::..|.|||.|.:||:|.||:||:|.||::||:||||.|::.|...:|....|
Zfish   154 NLPQVSIVFIFVNEALSVILRSIHSVMNRTPSHLLKEIILVDDNSNNDELKEKLQDFVKETNAKQ 218

  Fly   259 ---VRVIRNDKREGLVRSRVKGADAAVSSVLTFLDSHVECNEMWLEPLLERVREDPTRVVCPVID 320
               ::|:|:.::|||:||||.|..||.:.|:...|:|||.|..|.||:|:|::||.||::.|..|
Zfish   219 PGFIKVVRHSRQEGLIRSRVSGWRAASAPVVALFDAHVEFNIGWAEPILQRIKEDRTRIISPSFD 283

  Fly   321 VISMDNFQY--IGASADLRGGFDWNLIFKW-EYLSPSERAMRHNDPTTAIRTPMIAGGLFVIDKA 382
            .|..|.|:.  ...||.   ||||.|   | .||:|.:.....|:.|..||:|.:. |.||:|:.
Zfish   284 NIKYDTFEIEEYPLSAQ---GFDWEL---WCRYLNPPKSWWNLNNSTAPIRSPALI-GCFVVDRL 341

  Fly   383 YFNKLGKYDMKMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKRHPYTFPGGSGNVFARNT 447
            ||.::|..|..|:::||||:|:..||||||||:|::||:|:.|:.|...||| ...:.:| .||.
Zfish   342 YFAEIGLLDEGMEIYGGENVELGVRVWQCGGSVEVLPCARIAHIERAHKPYT-EDLTAHV-RRNA 404

  Fly   448 RRAAEVWMDDYKQHYYNAVPLAKNIP-------FGNIDDRLALKEKLHCKPFKWYLENVYPDLQA 505
            .|.||||||::|.|.|    :|.|||       .|:|.:|.||::||.||.|:|||.|:||:::.
Zfish   405 LRVAEVWMDEFKSHVY----MAWNIPQEDSGIDIGDIAERKALRKKLQCKTFRWYLVNIYPEMRM 465

  Fly   506 -PDPQEVGQFRQD-STE-CLDTMGHLIDGTVGIFPCHN-TGGNQEWAFTKR---GEIK-----HD 558
             .|....|..|.. .|: ||| .|...|....::.||. |..|..:..|::   |.:.     .|
Zfish   466 YTDTVAYGVLRNSLKTDLCLD-QGPDTDNIPILYLCHGMTPQNVYYTSTQQLFVGILSPTVDDDD 529

  Fly   559 DLCLTLVTFARGSQVVLKACDDSENQR----WIMREGGLVRHYKINVCLD--SRDQSQQG--VSA 615
            :.||..|    ..:..|..|..:..:|    |...:||.:::.|...||:  ..:.::.|  ::.
Zfish   530 NKCLVDV----NGRPRLIECSYAVAKRMKLHWRFTQGGSIQNTKSKRCLELVENNDNEFGFQLTL 590

  Fly   616 QHCNSALGTQRWS 628
            |.|..    |.|:
Zfish   591 QKCTG----QNWT 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	104/243 (43%)
		pp-GalNAc-T	205..500	CDD:133004	136/313 (43%)
		Ricin_B_lectin	511..627	CDD:279046	31/134 (23%)
		RICIN	513..629	CDD:238092	31/135 (23%)
galnt18b	XP_003199061.1	pp-GalNAc-T	159..460	CDD:133004	136/313 (43%)
		Glyco_tranf_2_2	160..421	CDD:287123	117/273 (43%)
		Ricin_B_lectin	471..598	CDD:279046	31/135 (23%)
		RICIN	473..600	CDD:238092	32/136 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810