DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpa and ptpa

DIOPT Version :9

Sequence 1:	NP_523466.2	Gene:	Ptpa / 33555	FlyBaseID:	FBgn0016698	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001003425.2	Gene:	ptpa / 445031	ZFINID:	ZDB-GENE-040801-11	Length:	324	Species:	Danio rerio

Alignment Length:	316	Identity:	145/316 - (45%)
Similarity:	209/316 - (66%)	Gaps:	8/316 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASGINQAAGKLPAIA--------KKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIF 58
            |||.:....|.|:..        |::..:.|||.|::|:|:.|.||:|...:..::|.|.|.|..
Zfish     7 ASGSSHEDDKPPSSVGFNFMVPKKEISMVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTCEYQ 71

  Fly    59 ESEMLKKLLRLFDALEKLVEQNPPLEQPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQVE 123
            .||.::|||.|...|::.:::.||::||.||||||:|.|...:.:....|:..:||.:::....|
Zfish    72 VSETVEKLLALLGTLDQWIDETPPVDQPSRFGNKAFRTWYAKLDQEAEALVAGVLPAERQDAAPE 136

  Fly   124 LGQYLTESFGNATRIDYGTGHELSFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTY 188
            :..||.||.||:||||||||||.:|..|||.|.|...|:..|.::....:|::||.:.|:||:||
Zfish   137 IAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKVGALRMEDQLAIIFNVFDKYLRVMRKLQKTY 201

  Fly   189 NMEPAGSQGVWSLDDFQFVPFIWGSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVK 253
            .||||||||||.||||||:||||||:||......:|..||:|.::.||...:||:.||.:|.::|
Zfish   202 RMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPTLEPRHFVEEKVVNEYHQDYMFLECIKFINEMK 266

  Fly   254 TGHFGEHSNQLWSITDVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPV 309
            ||.|.|||||||:|:.||:|:|:|.||::||:.|.|.|||||||..||.|::.:||
Zfish   267 TGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLSIQPV 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpa	NP_523466.2	PTPA	17..308	CDD:281137	138/290 (48%)
ptpa	NP_001003425.2	PTPA	28..321	CDD:281137	138/292 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594199
Domainoid	1	1.000	299	1.000	Domainoid score	I1413
eggNOG	1	0.900	-	-		E1_COG5057
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6149
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2642
OMA	1	1.010	-	-		QHG54183
OrthoDB	1	1.010	-	-		D1165705at2759
OrthoFinder	1	1.000	-	-		FOG0002736
OrthoInspector	1	1.000	-	-		oto41126
orthoMCL	1	0.900	-	-		OOG6_101438
Panther	1	1.100	-	-	LDO	PTHR10012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1030
SonicParanoid	1	1.000	-	-		X2111
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800