DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpa and CG8509

DIOPT Version :9

Sequence 1:	NP_523466.2	Gene:	Ptpa / 33555	FlyBaseID:	FBgn0016698	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_573079.1	Gene:	CG8509 / 32535	FlyBaseID:	FBgn0030696	Length:	432	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	125/316 - (39%)
Similarity:	188/316 - (59%)	Gaps:	17/316 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFESEMLKKLLRLFDALEKL-VEQN 80
            |:|::|.|:..|.:|:|::|:|.||:.||.||||.:.|.....:|.:::|..:||.|:.| ||..
  Fly    29 KQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFPVTEQMRRLSEIFDGLDHLIVEHT 93

  Fly    81 PPLEQPQ---RFG---NKAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRID 139
            |.:|...   .||   :||||.|.:.|.:.:...|::.:..:.|... ||||||..||||...:|
  Fly    94 PKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVNCKHIN-ELGQYLRRSFGNGNTLD 157

  Fly   140 YGTGHELSFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTYNM----EPAGSQGVWS 200
            :|..:||.||||||.||:|.||..:|.|:|||.|||||:.:.|:|..||.:    :||     .:
  Fly   158 FGPANELMFLFFLCGLFRAGILLAKDTVAAALMLFNRYVNVVRRLISTYGLTIAKDPA-----CT 217

  Fly   201 LDDFQFVPFIWGSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGHFGEHSNQLW 265
            ::|:.|:|::||:|||:|.|||.|.:.....|:..|:..||.:..||::.|.::|.....:.|||
  Fly   218 IEDYYFLPYLWGAAQLSVDSPFSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGPLSRVALQLW 282

  Fly   266 SITDVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPVSSGTTLSNARLG 321
            ||..:|||.::..||.:.|...:||.|..::...|.|||:||.|.....|..|.||
  Fly   283 SILSIPTWPQVYRGLERNYIDHVLSSFGTVEQAIFCELMSFEAVVPIMPLQRAHLG 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpa	NP_523466.2	PTPA	17..308	CDD:281137	119/301 (40%)
CG8509	NP_573079.1	PTPA	27..324	CDD:281137	118/300 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468029
Domainoid	1	1.000	198	1.000	Domainoid score	I581
eggNOG	1	0.900	-	-		E1_COG5057
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1048
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1165705at2759
OrthoFinder	1	1.000	-	-		FOG0002736
OrthoInspector	1	1.000	-	-		otm46691
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.800