DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpa and SPAC1782.05

DIOPT Version :9

Sequence 1:	NP_523466.2	Gene:	Ptpa / 33555	FlyBaseID:	FBgn0016698	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_594712.1	Gene:	SPAC1782.05 / 2542349	PomBaseID:	SPAC1782.05	Length:	352	Species:	Schizosaccharomyces pombe

Alignment Length:	324	Identity:	102/324 - (31%)
Similarity:	174/324 - (53%)	Gaps:	39/324 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFESEMLKKLLRLFDALEKLVEQNP 81
            :::.:..|:.::::..|:..:..:|.....|::....:..|.:|..::.:|.:.|.:.::.::||
pombe    15 RRILDNEDLKLFKEGDAYKLIDSFICDLDEAVKDKPISASIPQSSSIEHVLNILDRVGEIKQENP 79

  Fly    82 PLE-QPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQV---------ELGQYLTESFGNAT 136
            .:: ...||||.|::.:           .:|:..:..|.:||         |.|:|..|||||..
pombe    80 AIDNMGSRFGNPAFQSF-----------YDQVYIETPKLHQVFGIEHNAAMEAGRYFYESFGNRK 133

  Fly   137 RIDYGTGHELSFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSL 201
            |||||:||||.|:.:|..|.:..|..:.|..:..:|:|.:|:||.|.||..|.:|||||.|||.|
pombe   134 RIDYGSGHELYFMSWLLILKQLGIFTKNDYPALVVRVFVKYVELMRSLQIFYTLEPAGSHGVWGL 198

  Fly   202 DDFQFVPFIWGSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTG---HFGEHSNQ 263
            |||.|:||::|:|||.......|....|..|:...:..:|::..:.::.|:|..   .|  ||..
pombe   199 DDFHFLPFLFGAAQLVNHKYLRPKHVRDPEILEMCRADYMYLGYVYFLNKLKPSVSLRF--HSPM 261

  Fly   264 LWSITDVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPVSSGTTLSNARLGHVAPPP 327
            :..|:.|.||:|:|.|::|||:.|:|.|.|::||..||.|:   |.|.|          ::|.|
pombe   262 IDDISAVKTWSKVNEGMIKMYRAEVLGKLPIMQHYLFGHLI---PASPG----------MSPAP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpa	NP_523466.2	PTPA	17..308	CDD:281137	97/303 (32%)
SPAC1782.05	NP_594712.1	LAG1	2..352	CDD:227390	102/324 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5057
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6149
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54183
OrthoFinder	1	1.000	-	-		FOG0002736
OrthoInspector	1	1.000	-	-		otm47090
orthoMCL	1	0.900	-	-		OOG6_101438
Panther	1	1.100	-	-	O	PTHR10012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1030
SonicParanoid	1	1.000	-	-		X2111
TreeFam	1	0.960	-	-
	11	10.810