DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptpa and Ptpa

DIOPT Version :9

Sequence 1:	NP_523466.2	Gene:	Ptpa / 33555	FlyBaseID:	FBgn0016698	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001349662.1	Gene:	Ptpa / 110854	MGIID:	1346006	Length:	325	Species:	Mus musculus

Alignment Length:	298	Identity:	144/298 - (48%)
Similarity:	204/298 - (68%)	Gaps:	2/298 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFESEMLKKLLRLFDALEKLVEQNP 81
            |::..:.|||.|::|:|:.|.||:|...:..::|.|.|.:...||.::||:.|.|.|::.:::.|
Mouse    28 KEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKVSEAIEKLVALLDTLDRWIDETP 92

  Fly    82 PLEQPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHEL 146
            |::||.||||||||.|...:.:....|:..::|........|:..||.|:.||:||||||||||.
Mouse    93 PVDQPSRFGNKAYRTWYAKLDQEAENLVATVVPTHLAAAVPEVAVYLKEAVGNSTRIDYGTGHEA 157

  Fly   147 SFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIW 211
            :|..|||.|.|..:|:..|.|:...::|:||||:.|:||:||.||||||||||.||||||:||||
Mouse   158 AFAAFLCCLCKIGVLRVDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIW 222

  Fly   212 GSAQL-AVKSP-FDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGHFGEHSNQLWSITDVPTWA 274
            ||:|| ....| .:|..||||..::|....:||:.||.:|.::|||.|.|||||||:|:.||:|:
Mouse   223 GSSQLIGTNHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGPFAEHSNQLWNISAVPSWS 287

  Fly   275 KINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPVSSG 312
            |:|.||::||:.|.|.|||||||..||.|:...||:||
Mouse   288 KVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpa	NP_523466.2	PTPA	17..308	CDD:281137	140/292 (48%)
Ptpa	NP_001349662.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
Ptpa	NP_001349662.1	PTPA	26..319	CDD:308619	140/292 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848683
Domainoid	1	1.000	299	1.000	Domainoid score	I1448
eggNOG	1	0.900	-	-		E1_COG5057
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6149
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2605
Isobase	1	0.950	-	0	Normalized mean entropy	S1048
OMA	1	1.010	-	-		QHG54183
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002736
OrthoInspector	1	1.000	-	-		oto92824
orthoMCL	1	0.900	-	-		OOG6_101438
Panther	1	1.100	-	-	LDO	PTHR10012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1030
SonicParanoid	1	1.000	-	-		X2111
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740