DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15412 and CG44005

DIOPT Version :9

Sequence 1:	NP_001259996.1	Gene:	CG15412 / 33553	FlyBaseID:	FBgn0031528	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001097635.2	Gene:	CG44005 / 5740769	FlyBaseID:	FBgn0264747	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	84/381 - (22%)
Similarity:	147/381 - (38%)	Gaps:	146/381 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SVRSLSDS-ALAELANLLVSTIS------YAQYAPDVQLDINIVMVELNEYLAQLGATPNI---- 59
            ::|:|.|. .||::.:.|....|      |.:::|.:...:.:..|    .||..|  |:|
  Fly    21 NLRNLRDKLRLAQVDDYLGKAFSYHSRSDYKKFSPKIHFPVRLYRV----LLANCG--PSIVEFT 79

  Fly    60 -----YQDLLRVI-------LSSDYLDANMRFT-CLQ-MLLNCGVTFLMTEVFPFSYYEKILQVI 110
                 :.|||...       |.|..:.|.:|.: .|| .|||...:.:..|:       |:....
  Fly    80 CGSDTWSDLLAKSIAKYCPNLESVNISATLRNSHSLQFFLLNLANSLISVEL-------KLNDSC 137

  Fly   111 AAQGAGLRVLNIKGIWVKE-EHM-HYMYD--IVRKCKQLVKLYVPYIANDRLLEEI-------GN 164
            .:.    |:||.    |.| :|: .::|:  |.|...||.||..        |||:       |.
  Fly   138 QSP----RILNA----VAELKHLKKFLYEGYIDRGVNQLCKLVD--------LEELQLIYQGRGY 186

  Fly   165 CCTRLQILDISGETDITEIGIDLLAKGVCSQSLTVVDVGMPGEENI---------------CYSD 214
            .|..:.:|.|.|  ::|.:           :.|||.::.:...|:.               |  :
  Fly   187 RCRAVNLLQICG--NMTNL-----------RRLTVSNISISQPESFHPMIWPNLKDLKMQNC--E 236

  Fly   215 IALILEHCPQVETLSTYSFVGASLKFIHDNVDDRFKCRLK-----YIHDTGTD------------ 262
            |:.::..||:::||        .:||.        |||:|     :|...|.:
  Fly   237 ISTVMPDCPKLKTL--------YIKFC--------KCRIKGYVCSFILKNGNNIEEIDESCEPAP 285

  Fly   263 ---EATLQVIMQTCPRLETLYLDSPKTGSLRALSTRNLRKLKIYKFVVAELLPLLE 315
               ::.|||| ::||:|:.|   |.:.|.           :|||:..|..::.:|:
  Fly   286 FDGQSFLQVI-RSCPKLQVL---STQMGG-----------IKIYQAFVTSVVDILK 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15412	NP_001259996.1	AMN1	<142..>228	CDD:187754	21/107 (20%)
		leucine-rich repeat	145..168	CDD:275381	8/29 (28%)
		leucine-rich repeat	169..196	CDD:275381	4/26 (15%)
		leucine-rich repeat	197..224	CDD:275381	7/41 (17%)
		leucine-rich repeat	225..252	CDD:275381	5/26 (19%)
		leucine-rich repeat	253..275	CDD:275381	8/41 (20%)
		leucine-rich repeat	369..393	CDD:275381
		leucine-rich repeat	394..416	CDD:275381
CG44005	NP_001097635.2	leucine-rich repeat	174..202	CDD:275380	8/29 (28%)
		leucine-rich repeat	203..226	CDD:275380	4/33 (12%)
		leucine-rich repeat	227..246	CDD:275380	3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR16134
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100