Protein Alignment CG15412 and Fbxl17

DIOPT Version :10

• Sequence 1: NP_001259996.1
• Gene: CG15412 / 33553
• FlyBaseID: FBgn0031528
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_056609.1
• Gene: Fbxl17 / 50758
• MGIID: 1354704
• Length: 701
• Species: Mus musculus
• Alignment Length: 363
• Identity: 76/363 - (20%)
• Similarity: 144/363 - (39%)
• Gaps: 98/363 - (26%)

  Fly   145 LVKLYVPYIANDRLLEEIGNC------CTRLQI---LDISGETDITEIGIDLLAKGVCSQSLTVV 200
            |:|::.....|:|.|.....|      |...|.   ||:|....:|:   :||.| :.|:|..::
Mouse   329 LLKIFSNLSLNERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTD---ELLEK-IASRSQNII 389

  Fly   201 DVGMPGEENICYSDIALILEHCP--------QVETLSTYSFVGAS-----LKFIHDNVDDRF--- 249
            ::.:....::..|.:.::...||        :.:.||..|.:..:     |:.:|....|:.
Mouse   390 EINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDE 454

  Fly   250 -------KCR-LKYIHDTG-----TDEATLQVIMQTCPRLETLYLDSPK---TGSLRALSTRNLR 298
                   :|| ||.|| .|     :||..: ||.::|.:|:.:|:...|   ..|::|.: .:..
Mouse   455 GLKQLGSRCRELKDIH-FGQCYKISDEGMI-VIAKSCLKLQRIYMQENKLVTDQSVKAFA-EHCP 516

  Fly   299 KLKIYKFVVAELLPLLERPIGRNLRHLTMIKGLGNLELGKLARL-----------CPSLIDLD-C 351
            :|:...|:...:       ..:.:.|||.::.|.:|:|..:..|           |.:|..|: |
Mouse   517 ELQYVGFMGCSV-------TSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLC 574

  Fly   352 --YMIDSLSYGAGHAKFQQLEGLEILSSAILTSSLKAFLCNSTDLKRLAVDTVEFTDDDIMSMFM 414
              ::|:.........:.|.|:.|.::|            |..||...:|:.....|.:.:
Mouse   575 LNWIINDRCVEVIAKEGQNLKELYLVS------------CKITDYALIAIGRYSVTIETV----- 622

  Fly   415 QHDFKVLEDV-WFTLAPELTVQSVELLMDSCPELQSVG 451
                    || |   ..|:|.|...|:..|...|:.:|
Mouse   623 --------DVGW---CKEITDQGATLIAQSSKSLRYLG 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15412	NP_001259996.1	AMN1	<142..>228	CDD:187754	20/99 (20%)
		leucine-rich repeat	145..168	CDD:275381	7/28 (25%)
		leucine-rich repeat	169..196	CDD:275381	9/29 (31%)
		leucine-rich repeat	197..224	CDD:275381	3/34 (9%)
		leucine-rich repeat	225..252	CDD:275381	6/41 (15%)
		leucine-rich repeat	253..275	CDD:275381	10/26 (38%)
		leucine-rich repeat	369..393	CDD:275381	4/23 (17%)
		leucine-rich repeat	394..416	CDD:275381	2/21 (10%)
Fbxl17	NP_056609.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..93
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..250
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	279..321
		F-box_FBXO13	320..368	CDD:438864	10/38 (26%)
		leucine-rich repeat	362..387	CDD:275381	9/28 (32%)
		leucine-rich repeat	388..413	CDD:275381	2/24 (8%)
		AMN1	411..573	CDD:187754	37/171 (22%)
		leucine-rich repeat	414..439	CDD:275381	3/24 (13%)
		leucine-rich repeat	440..465	CDD:275381	4/24 (17%)
		leucine-rich repeat	466..491	CDD:275381	10/26 (38%)
		leucine-rich repeat	492..517	CDD:275381	5/25 (20%)
		leucine-rich repeat	545..567	CDD:275381	4/21 (19%)
		leucine-rich repeat	568..593	CDD:275381	4/24 (17%)
		leucine-rich repeat	594..618	CDD:275381	7/35 (20%)
		leucine-rich repeat	619..644	CDD:275381	8/40 (20%)
		leucine-rich repeat	645..670	CDD:275381	2/5 (40%)