DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15412 and CG5003

DIOPT Version :9

Sequence 1:	NP_001259996.1	Gene:	CG15412 / 33553	FlyBaseID:	FBgn0031528	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_651593.1	Gene:	CG5003 / 43344	FlyBaseID:	FBgn0039554	Length:	713	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	61/285 - (21%)
Similarity:	95/285 - (33%)	Gaps:	88/285 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 DRLLEEIGNCCTRLQILDISGETDITEIG---------------IDL----LAKGVCSQSL---- 197
            |.||.||      .|.||.|....:....               |||    |..|:..:.|
  Fly    74 DELLFEI------FQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRAT 132

  Fly   198 ----TVVDVGMPGEENIC--YSDIALILEHC-PQVETLSTYSFVGASLKFIHDNVDDRFKCRLKY 255
                |:...|.|..:::.  :......|... |:|..|......|.||.|             :|
  Fly   133 EKTHTIKICGPPSSQHVAGEFRQFTQTLSSVFPRVVQLKVLELEGVSLDF-------------EY 184

  Fly   256 IHDTGTDEATLQVIMQTCPRLETLYLDSPKTGSLRALSTRNLRKLKIYKFVVAELLPLLERPIGR 320
            ||.|.......::.::.|   .....|:||:               |:..:...||.|.:..|..
  Fly   185 IHITEFPATLRRLKLKDC---SVRVGDTPKS---------------IFYSIELHLLDLEDLSIED 231

  Fly   321 N-------LRHLTMIKGLGNLELGKLARLCPSLIDLDCYMIDSLSYGAGHAK--FQQLEGLEILS 376
            |       :..|:.:..|..|.|.....||           ..:.||:..|:  ||:||.|::..
  Fly   232 NSWFEPYYIMGLSKLPSLRRLSLKGCQALC-----------KFVPYGSMAARFGFQKLESLDLRQ 285

  Fly   377 SAILTSSLKAFLCNSTDLKRLAVDT 401
            :.|..|.|:.|.. ..:||.|.:::
  Fly   286 TPINNSDLQCFSA-IENLKELLLES 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15412	NP_001259996.1	AMN1	<142..>228	CDD:187754	21/101 (21%)
		leucine-rich repeat	145..168	CDD:275381	5/11 (45%)
		leucine-rich repeat	169..196	CDD:275381	9/45 (20%)
		leucine-rich repeat	197..224	CDD:275381	5/37 (14%)
		leucine-rich repeat	225..252	CDD:275381	6/26 (23%)
		leucine-rich repeat	253..275	CDD:275381	5/21 (24%)
		leucine-rich repeat	369..393	CDD:275381	7/23 (30%)
		leucine-rich repeat	394..416	CDD:275381	3/8 (38%)
CG5003	NP_651593.1	F-box	68..114	CDD:279040	10/45 (22%)
CG5003	NP_651593.1	leucine-rich repeat	610..635	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR16134
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100