DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15412 and Fbxl22

DIOPT Version :9

Sequence 1:	NP_001259996.1	Gene:	CG15412 / 33553	FlyBaseID:	FBgn0031528	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001102239.1	Gene:	Fbxl22 / 363083	RGDID:	1311830	Length:	236	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	59/232 - (25%)
Similarity:	90/232 - (38%)	Gaps:	66/232 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LLRVILSSDYLDANMR----FTCLQM-----------LLNC-GVTFLMTEVFPFSYYEKILQVIA 111
            |||:.   .:||.:.|    .||.|:           ||:. .:|.|..:.|..|...:.|. |.
  Rat    11 LLRLF---SFLDKDSRKSLSRTCSQLRDVFEDPTLWSLLHFHSLTELKKDNFRLSPALRSLS-IC 71

  Fly   112 AQGAGLRVLNIKGIWVKEEHMHYMYDIVRKCKQLVKLYVPYIANDRLLEEIGNCCTRLQILDISG 176
            ...:.::|.:|:. |:|......:      |.|...|     .||.|| ::.|.|..|..:.:||
  Rat    72 WHSSRVQVCSIED-WLKSAFQRSI------CSQHENL-----VNDFLL-QVCNRCPNLASVTLSG 123

  Fly   177 ETDITEIGIDLLAKGVCSQSLTVVDVGMPGEENICYSDIALILEHCPQV--ETLSTYSFVGASLK 239
            ...:|:   |.||:         :.:|.|...       ||.||:|.:|  .||:..:..|.:|:
  Rat   124 CGHVTD---DCLAR---------LLLGCPRLR-------ALRLENCARVTNRTLAAVAAHGRALQ 169

  Fly   240 FIHDNVDDRFKCRLKYIHDTGTDEATLQVIMQTCPRL 276
            ..|  ||   .||       ....|.|..:...||.|
  Rat   170 TFH--VD---FCR-------NVSAAGLLRLRAACPNL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15412	NP_001259996.1	AMN1	<142..>228	CDD:187754	24/87 (28%)
		leucine-rich repeat	145..168	CDD:275381	7/22 (32%)
		leucine-rich repeat	169..196	CDD:275381	7/26 (27%)
		leucine-rich repeat	197..224	CDD:275381	7/26 (27%)
		leucine-rich repeat	225..252	CDD:275381	8/28 (29%)
		leucine-rich repeat	253..275	CDD:275381	3/21 (14%)
		leucine-rich repeat	369..393	CDD:275381
		leucine-rich repeat	394..416	CDD:275381
Fbxl22	NP_001102239.1	F-box-like	3..43	CDD:403981	9/34 (26%)
		AMN1	44..>191	CDD:187754	47/191 (25%)
		leucine-rich repeat	116..141	CDD:275381	8/36 (22%)
		leucine-rich repeat	142..167	CDD:275381	9/31 (29%)
		leucine-rich repeat	168..193	CDD:275381	9/36 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16134
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100