Protein Alignment CG15412 and Skp2

DIOPT Version :10

• Sequence 1: NP_001259996.1
• Gene: CG15412 / 33553
• FlyBaseID: FBgn0031528
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001099886.1
• Gene: Skp2 / 294790
• RGDID: 1562456
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 369
• Identity: 76/369 - (20%)
• Similarity: 128/369 - (34%)
• Gaps: 120/369 - (32%)

  Fly   138 IVRKCKQLVKLYVPYIANDRLLEE----------------IGNCCTR----------LQILDISG 176
            |:|:.| |.:...|.::.|.|.:|                :...|.|          .|.||::|
  Rat    81 IIRRPK-LNRENFPGVSWDSLPDELLLGIFSCLCLPELLRVSGVCKRWYRLSLDESLWQSLDLAG 144

  Fly   177 ETDITEIGIDLLAKGV----CSQSLTVVDVGMP-----------GEENICYSDIALILEHCPQVE 226
            :....::.:.||::||    |.:|.....:|..           ....|..|::..||..|.:::
  Rat   145 KNLHPDVTVRLLSRGVVAFRCPRSFMEQPLGESFSSFRVQHMDLSNSVINVSNLHGILSECSKLQ 209

  Fly   227 TLSTYSFVGASLK--FIHDNVDDRFKCRLKYIHDTGTDEATLQVIMQTCPRLETLYLDSPKTGSL 289
            .|   |..|..|.  .:.....:....||.....:|..|:.:..::.:|.||:.|.|
  Rat   210 NL---SLEGLQLSDPIVTTLAQNENLVRLNLCGCSGFSESAVATLLSSCSRLDELNL-------- 263

  Fly   290 RALSTRNLRKLKIYKFVVAELLPLLERPIGRNLRH----LTMI------KGLGNLELGKLARLCP 344
                              :......|:.:...:.|    ||.:      |.|...:|..|.:.||
  Rat   264 ------------------SWCFDFTEKHVQAAVAHLPDTLTQLNLSGYRKNLQKTDLCTLIKRCP 310

  Fly   345 SLIDLDCYMIDSLSY-GAGHAKFQQLEGLEILSSA----ILTSSLKAFLCNSTDLKRLAVDTVEF 404
            :|:.||  :.||:.. .....:|.||..|:.||.:    |:..:|.. |.....||.|.|
  Rat   311 NLVRLD--LSDSIMLKNDCFPEFFQLNYLQHLSLSRCYDIIPETLLE-LGEIPTLKTLQV----- 367

  Fly   405 TDDDIMSMFMQHDFKVLEDVWFTLAPELTVQSVELLMDSCPELQ 448
                                 |.:.|:.|:|   ||.::.|.||
  Rat   368 ---------------------FGIVPDGTLQ---LLREALPRLQ 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15412	NP_001259996.1	AMN1	<142..>228	CDD:187754	24/126 (19%)
		leucine-rich repeat	145..168	CDD:275381	6/38 (16%)
		leucine-rich repeat	169..196	CDD:275381	9/30 (30%)
		leucine-rich repeat	197..224	CDD:275381	6/37 (16%)
		leucine-rich repeat	225..252	CDD:275381	4/28 (14%)
		leucine-rich repeat	253..275	CDD:275381	4/21 (19%)
		leucine-rich repeat	369..393	CDD:275381	7/27 (26%)
		leucine-rich repeat	394..416	CDD:275381	4/21 (19%)
Skp2	NP_001099886.1	F-box_FBXL1	97..137	CDD:438886	5/39 (13%)
		leucine-rich repeat	137..167	CDD:275381	9/29 (31%)
		leucine-rich repeat	183..207	CDD:275381	5/23 (22%)
		AMN1	193..>345	CDD:187754	39/182 (21%)
		leucine-rich repeat	208..231	CDD:275381	4/25 (16%)
		leucine-rich repeat	232..257	CDD:275381	5/24 (21%)
		leucine-rich repeat	258..283	CDD:275381	5/50 (10%)
		leucine-rich repeat	285..311	CDD:275381	7/25 (28%)
		leucine-rich repeat	312..336	CDD:275381	8/25 (32%)
		leucine-rich repeat	337..356	CDD:275381	5/19 (26%)