Protein Alignment CG15412 and Skp2

DIOPT Version :10

• Sequence 1: NP_001259996.1
• Gene: CG15412 / 33553
• FlyBaseID: FBgn0031528
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_011243661.1
• Gene: Skp2 / 27401
• MGIID: 1351663
• Length: 434
• Species: Mus musculus
• Alignment Length: 365
• Identity: 75/365 - (20%)
• Similarity: 128/365 - (35%)
• Gaps: 112/365 - (30%)

  Fly   138 IVRKCKQLVKLYVPYIANDRLLEE----------------IGNCCTR----------LQILDISG 176
            |:|:.| |.:...|.::.|.|.:|                :...|.|          .|.||::|
Mouse    91 IIRRPK-LSRENFPGVSWDSLPDELLLGIFSCLCLPELLRVSGVCKRWYRLSLDESLWQSLDLAG 154

  Fly   177 ETDITEIGIDLLAKGV----CSQSLTVVDVGMP-----------GEENICYSDIALILEHCPQVE 226
            :....::.:.||::||    |.:|.....:|..           ....|..|::..||..|.:::
Mouse   155 KNLHPDVTVRLLSRGVVAFRCPRSFMEQPLGESFSSFRVQHMDLSNSVINVSNLHKILSECSKLQ 219

  Fly   227 TLSTYSFVGASLK--FIHDNVDDRFKCRLKYIHDTGTDEATLQVIMQTCPRLETLYLDSPKTGSL 289
            .|   |..|..|.  .:.....:....||.....:|..|:.:..::.:|.||:.|.|
Mouse   220 NL---SLEGLQLSDPIVKTLAQNENLVRLNLCGCSGFSESAVATLLSSCSRLDELNL-------- 273

  Fly   290 RALSTRNLRKLKIYKFVVAELLPLLERPIGRNLRHL----TMI------KGLGNLELGKLARLCP 344
                              :......|:.:...:.||    |.:      |.|...:|..:.:.||
Mouse   274 ------------------SWCFDFTEKHVQAAVAHLPNTITQLNLSGYRKNLQKTDLCTIIKRCP 320

  Fly   345 SLIDLDCYMIDSLSY-GAGHAKFQQLEGLEILSSAILTSSLKAFLCNSTDLKRLAVDTVEFTDDD 408
            :||.||  :.||:.. .....:|.||..|:.||                 |.|    ..:...|.
Mouse   321 NLIRLD--LSDSIMLKNDCFPEFFQLNYLQHLS-----------------LSR----CYDIIPDT 362

  Fly   409 IMSMFMQHDFKVLEDVWFTLAPELTVQSVELLMDSCPELQ 448
            ::.:......|.|:  .|.:.||.|:|   ||.::.|.||
Mouse   363 LLELGEIPTLKTLQ--VFGIVPEGTLQ---LLREALPRLQ 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15412	NP_001259996.1	AMN1	<142..>228	CDD:187754	24/126 (19%)
		leucine-rich repeat	145..168	CDD:275381	6/38 (16%)
		leucine-rich repeat	169..196	CDD:275381	9/30 (30%)
		leucine-rich repeat	197..224	CDD:275381	6/37 (16%)
		leucine-rich repeat	225..252	CDD:275381	4/28 (14%)
		leucine-rich repeat	253..275	CDD:275381	4/21 (19%)
		leucine-rich repeat	369..393	CDD:275381	4/23 (17%)
		leucine-rich repeat	394..416	CDD:275381	3/21 (14%)
Skp2	XP_011243661.1	F-box_FBXL1	107..147	CDD:438886	5/39 (13%)
		leucine-rich repeat	147..177	CDD:275381	9/29 (31%)
		leucine-rich repeat	193..217	CDD:275381	5/23 (22%)
		LRR	<194..>379	CDD:443914	44/238 (18%)
		leucine-rich repeat	218..241	CDD:275381	4/25 (16%)
		leucine-rich repeat	242..267	CDD:275381	5/24 (21%)
		leucine-rich repeat	268..293	CDD:275381	6/50 (12%)
		leucine-rich repeat	295..321	CDD:275381	5/25 (20%)
		leucine-rich repeat	322..346	CDD:275381	9/25 (36%)
		leucine-rich repeat	347..366	CDD:275381	6/39 (15%)