Protein Alignment GramD1B and YSP2

DIOPT Version :9

• Sequence 1: NP_995623.2
• Gene: GramD1B / 33552
• FlyBaseID: FBgn0085423
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: NP_010613.1
• Gene: YSP2 / 851926
• SGDID: S000002734
• Length: 1438
• Species: Saccharomyces cerevisiae
• Alignment Length: 1201
• Identity: 252/1201 - (20%)
• Similarity: 432/1201 - (35%)
• Gaps: 330/1201 - (27%)

  Fly     3 KEDIKKP---PRKTLNVDAKKAKRKKMIKDSDKINPTTSSVN------ITVTTAESSSSCKNPA- 57
            |..:|||   |:...|:.....:..:.:|.:|..|...||.:      :::...:.|.|..:||
Yeast   148 KAGLKKPNTSPQGYFNIPVTIDRASEKVKHTDTKNTFNSSSSENERPVLSILQKDDSQSSSHPAI 212

  Fly    58 ----------NANMIPETTQP--DQLQS---------------QTQTQAQLQPQSQSPS------ 89
                      |.|.|..::..  |.:.|               .|:.|.:.....:|.:
Yeast   213 DSMSAPNNINNNNDIENSSNSLFDTILSIAHSAISHVPKISALNTEIQREFSHSGESHTGSTRHP 277

  Fly    90 --QCQQAQENPEHLQQQ----------SQPEEELQAEAPGSNAGDRRDSITEEIT-ITSTTNSSQ 141
              ....||:.....|||          ..|.:.:...:|.:|...|..|....:. :.|.|:...
Yeast   278 YFHIHHAQQQHPLSQQQGPLPVSENANQNPNDTVLIHSPSANTAHRSSSFLRHLDYLLSPTSGPA 342

  Fly   142 STKLLTIQEAAGSFEQSSVS-AVSTSSKQIASTTAGGSP-------------------------- 179
            |.|...::|.....|.|.:| |..:.|.|:..|....:|
Yeast   343 SDKHTQVEEGDDEEELSPLSKAFLSPSTQLVPTNTSTTPLSGSLTPNNRNVNANSNSETENDNDR 407

  Fly   180 ------------------PA-----------AAAPGANEFNGSVLRLTQAATSTSPGS------- 208
                              ||           .|..|:::.:.:.:.|.:..|:.:|.:
Yeast   408 DDRSNVGKVKFQPLKVHEPAISTFGKGNLTLEAVAGSSDIDNTTIDLDENNTNNNPNASSTNLSH 472

  Fly   209 ISSAGNTATLGAAP------------------SINIVSSESTRDQTQQPQSVDPNGVAAPGDSP- 254
            ||.:.....||...                  |.:.:||...|.:|........|.|...|:|.
Yeast   473 ISKSNVNNNLGPKELNTSYRNSTYIDMARFENSQSNLSSHRARSKTLPANKALENAVGDEGNSKR 537

  Fly   255 SSRKSSTSSK---GKASQAKL-STSSSGRDEQDISQHRLSDLTQHELSLLRVDREQQVTSSSSTS 315
            :||.||.|:.   ..|.:.|. |.|....:.:..|...|.:.....::|.....:.:.:||...|
Yeast   538 NSRYSSYSNDMAFDDADERKFRSMSKKFLNRRSFSPSNLGNKVIPGINLRNSFNKNRNSSSDFFS 602

  Fly   316 NEKPAKTSRLSERAKKK--------------SWYNVIYPNYKSRAEDFKKLFKDV---PNDERLI 363
            ..:..:..|.|......              ....:.|.:.|..:| |..||||.   || |:||
Yeast   603 TNQGQQMPRTSTAGSGNIHAIMGLDSGNDDFKLEGIEYASEKKNSE-FHTLFKDCDINPN-EKLI 665

  Fly   364 VDYSCALQRDILVQGRLYVSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSG 428
            ||:||||.||||:|||:|:|..::.|.:||..|.:.|.|.:|::..|.|:.||.:.||.|.|.:.
Yeast   666 VDHSCALSRDILLQGRMYISDAHIGFFSNILGWVSTVFIPFKEIVQIEKKTTAGIFPNGIVIDTL 730

  Fly   429 KDKYFFATFTSRDKSFLMLFRVWQNTLMNKQF------SPQEIWQHVHTCYGDELGLTTDDEDY- 486
            ..||.||:|.|||.:|.::..||...::.|::      :.........:.:.|:.....||.|.
Yeast   731 HTKYIFASFMSRDATFDLITDVWNQIILGKKYRNGFGNNDDGTISDSSSAFFDDSDDNDDDGDLD 795

  Fly   487 -IDPTLNKTNEPDFDFQTAIDDDSYSQRQSQQSNQSNQSNPLL------PQSGNSSASSGGGV-- 542
             .||.:|.|   |......||.|.:::......||.: :|.||      |.:.:...|:...:
Yeast   796 DDDPDINST---DMTSSDDIDADVFNESNDLGKNQKS-TNYLLGPNKHSPTTADFKPSNNDHLVI 856

  Fly   543 --RASAP--------RKSKTKYFFNSSKSSANASASGSDNNKTRESSRKLNKKMKQNAKELTLS- 596
              ..:||        ......|:....|:..|...|...||       .|.||::..|....||
Yeast   857 EANINAPLGKVVNLLYGEDVSYYERILKAQKNFEISPIPNN-------FLTKKIRDYAYTKPLSG 914

  Fly   597 SVKPTELS------------------VSVTMSAPNVSSSSTAGSTTASSSTIANHTGSGSGSGSL 643
            |:.|::..                  :|:|.: |:|.|.:     ..|..|:...:...:.|..|
Yeast   915 SIGPSKTKCLITDTLEHYDLEDYVKVLSITKN-PDVPSGN-----IFSVKTVFLFSWDKNNSTKL 973

  Fly   644 SGSNTAAASGSGSDKMSAEK-KVSTASNSAAVAAAEAAQSLASASSGSGSLESKMEMKRKLGKMH 707
            :..|:...:|....|...|| .....:::..:..:|..:.|:...|   ::.||.:
Yeast   974 TVYNSVDWTGKSWIKSMIEKGTFDGVADTTKIMISEIKKILSDEDS---NINSKHQ--------- 1026

  Fly   708 RQREEGKNAAESVPTDVSDSSDSEEN--NLPFV--PTTECTSTHEGRQIVHTI------LPINVD 762
                             :.:::|||.  |||.:  |..:.|.....:....|:      :|:.:.
Yeast  1027 -----------------ASNNESEEEIINLPTIGPPVHDPTEPDFQKGKDDTVIDEKINIPVPLG 1074

  Fly   763 TLFNLLFSKSKFITDFHAMRKSTDLVLGEWTKNEEGLQV----------RTVNVTVQLAASVGPK 817
            |:|:||:.     .|...::|..:        |:....|          |.:..|.:|..|.|||
Yeast  1075 TVFSLLYG-----DDTSYIKKIIE--------NQNNFNVCDIPKFVNNAREITYTKKLNNSFGPK 1126

  Fly   818 TSK--VTEYQTQRECSKPGELYSIDVNSV--------NAGIPYAESFSVLIHFCLARTVDDHTML 872
            .:|  |||           .:..:|:||.        :..:||..||||...|..:....:.|.:
Yeast  1127 QTKCIVTE-----------TIEHMDLNSFFMVKQIVRSPDVPYGSSFSVHTRFFYSWGDHNTTNM 1180

  Fly   873 SIHTQIKYKKSIW---GVVKGFIEKNTWAG--------LEDFFGAQLHALQSETCIPPAKGKGRR 926
            .:.|.:     :|   .::||.|||.:..|        ::|.  .::.:..|.|     |.|.||
Yeast  1181 KVVTNV-----VWTGKSMLKGTIEKGSIDGQRSSTKQLVDDL--KKIISNASST-----KKKSRR 1233

  Fly   927 PRRGMNQQSATSTSTTSITTGALHTATSTDN 957
            ..:.:|::.::.::..:.........|||.|
Yeast  1234 RGKTVNKRKSSPSTIKNEKNEENFEDTSTKN 1264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GramD1B	NP_995623.2	PH-GRAM_GRAMDC	358..451	CDD:275406	43/92 (47%)
		DUF4782	751..897	CDD:292635	39/174 (22%)
YSP2	NP_010613.1	PH-GRAM_GRAMDC	660..753	CDD:275406	44/93 (47%)
		DUF4782	854..998	CDD:406424	30/156 (19%)
		DUF4782	1062..1205	CDD:406424	38/171 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343614
Domainoid	1	1.000	100	1.000	Domainoid score	I1558
eggNOG	1	0.900	-	-		E1_KOG1032
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46922
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23319
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1861
SonicParanoid	1	1.000	-	-		X567
TreeFam	1	0.960	-	-
	10	9.830