Protein Alignment GramD1B and gramd1ba

DIOPT Version :9

• Sequence 1: NP_995623.2
• Gene: GramD1B / 33552
• FlyBaseID: FBgn0085423
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: XP_021335128.1
• Gene: gramd1ba / 568698
• ZFINID: ZDB-GENE-091118-87
• Length: 882
• Species: Danio rerio
• Alignment Length: 1194
• Identity: 304/1194 - (25%)
• Similarity: 489/1194 - (40%)
• Gaps: 378/1194 - (31%)

  Fly    84 QSQSPSQCQQAQENPEHLQQQSQP------------------EEELQAEAPGSNAGDRRDSITEE 130
            |.|.| :|..::.:| :|...|.|                  :|:|:.|.
Zfish    11 QIQGP-ECNGSEVDP-NLSSSSSPALRRKRFKMRRMKNVMSEKEQLEKEQ--------------- 58

  Fly   131 ITITSTTNSSQSTKLLTIQEAAGSFEQSSVSAVSTSSKQIASTTAGGSPPAAAAPGANEFNGSVL 195
               ...:.|.:..:|.:|:....|.|.::.|:.||.|               |:|....|   :|
Zfish    59 ---LQRSGSKEYLQLPSIEITPSSDEDAAWSSCSTPS---------------ASPQRRRF---LL 102

  Fly   196 R-LTQAATSTSPGSISSAGNTATLGAAPSINIVSSESTR---DQTQQPQSVDPNGVAAPGDSPSS 256
            | ..:.......||.||:..::...:.      ..||||   ..|::..:...:..:.|..||..
Zfish   103 RKWLRGGEKKEHGSESSSQQSSLQSSH------EEESTRYLSPNTREDSTASNSNRSTPACSPVL 161

  Fly   257 RKSSTSSKGKASQAKLSTSSSGRDEQDISQHRLSDLTQHELSLLRVDREQQVTSSSSTSNEKPAK 321
            ||.|.|...::.:.:...........|.|.      :..|.::.|...:...|:.:...|.|..|
Zfish   162 RKRSRSPTPQSPEGENMVEKGSDHSSDKSP------STPEPAVQRTYSQSLHTTRTGGKNSKSHK 220

  Fly   322 TSRLSERAKKKSWYNVIYPNYKSRAEDFKKLFKDVPNDERLIVDYSCALQRDILVQGRLYVSQNY 386
              |||:  |.:|||||:.|.||.|.|||:||||.:|:.||||||||||||||||:|||||:|:|:
Zfish   221 --RLSK--KSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENW 281

  Fly   387 VCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSGKDKYFFATFTSRDKSFLMLFRVW 451
            :||::|||.|||.::::.|||.::||||||.:|||||.:.:..:|:||.:|.:||::::|:||:|
Zfish   282 ICFYSNIFRWETLLTVRLKDVCSMTKEKTARLIPNAIQLCTDNEKHFFTSFGARDRTYMMMFRLW 346

  Fly   452 QNTLMNKQFSPQEIWQHVHTCYGDELGLTTDDEDYIDPTLNKTNEPDFDFQTAIDDDSYSQRQSQ 516
            ||.|::|...|:|:|..||.|||:|||||:|||||:        .||.||.|.    .|.:....
Zfish   347 QNALLDKPLCPKELWHFVHQCYGNELGLTSDDEDYV--------PPDDDFNTM----GYCEEIPA 399

  Fly   517 QSNQSNQSNPLLPQSGNSSASSGGGVRASAPRKSKTKYFFNSSKSSANASASGSDN-NKTRES-- 578
            :.|::|                                                || |||.::
Zfish   400 EDNEAN------------------------------------------------DNCNKTPDAKM 416

  Fly   579 --SRKLNKKMKQNAKELTLSSVKPTELSVSVTMSAPNVSSSSTAGSTTASSSTIANHTGSGSGSG 641
              |.:|::|:..|:   :|:|...|:  ..:....|.|...:..........|:
Zfish   417 DISPQLHRKVFPNS---SLNSTDSTD--APLNFDVPPVEDFTNCIPEDLLPLTL----------- 465

  Fly   642 SLSGSNTAAASGSGSDKMSAEKKVSTASNSAAVAAAEAAQSLASASSGSGSLESKMEMKRKLGKM 706
                               .:.|:|....||.|.|.            |.||:.
Zfish   466 -------------------PDNKLSETGGSAHVPAP------------SPSLDF----------- 488

  Fly   707 HRQREEGKNAAESVPTDVSDSSDSEENNLPFVPTTECTSTHE---GRQIVHTILPINVDTLFNLL 768
                    |..|.:||::||||::.:..       |..:..|   |:..::.:...:||.|.::|
Zfish   489 --------NDNEDLPTELSDSSETHDEG-------EVQAFQEDLNGKLYINEVYKFSVDKLHDIL 538

  Fly   769 FSKSKFITDFHAMRKSTDLVLGEWTKNEEGLQVRTVNVTVQLAASVGPKTSKVTEYQTQRECSKP 833
            |::|:|:.:|...|:.:|:|...|.|.:.|.|.|.:..|:.|:..:.|||:.|||.||..:.|:.
Zfish   539 FTESQFMREFLEQRRFSDVVYHPWRKEDTGNQTREIMYTISLSNPLAPKTATVTETQTLHKASQV 603

  Fly   834 GELYSIDVNSVNAGIPYAESFSVLIHFCLARTVDDHTMLSIHTQIKYKKSIWGVVKGFIEKNTWA 898
            .|.|.||...:...:||.:.|..|..:.|.|...:...|.:..:::|:|..||:||||||:|.|:
Zfish   604 SECYIIDAEVIAHDVPYHDYFYTLNRYMLTRVARNKCRLRVSAELRYRKQPWGLVKGFIERNFWS 668

  Fly   899 GLEDFFGAQLHALQSETCIPPAKGKGRRPRRGMNQQSATSTSTTSITTGALHTATSTDNDSIQES 963
            ||:::|    ..|:.|.         .:.:..:::||..|.        ||.|||      ::..
Zfish   669 GLDEYF----RYLELEL---------NKVQLVLSEQSPKSK--------ALRTAT------VRRR 706

  Fly   964 RHPHQQDQHQHQHLHMHHHHHHHHGSQHHHHDARHSHHHHHQPLLPHHQQQHPHHWHHRKALLQS 1028
            :.|                                         |.|.:.||
Zfish   707 KRP-----------------------------------------LTHMRPQH------------- 717

  Fly  1029 GRGTATQIRPLEEAVGPAPAVDPLETQMLAAGGIPGAAVGAAAGHPLLLEGGKQQQLHHQQQMHH 1093
                      ::||:.|....:..::.:                         |:..|.......
Zfish   718 ----------MDEALSPVTTPEDEKSVI-------------------------QRIKHVAGSTQT 747

  Fly  1094 HHLQPHKQHLQQQQLHLGGGDGQPLASGQGSQGHRLRHKGLWLLVI-----LLLCLMLALNVILL 1153
            .|:..|                       .|:|..|......||:|     :.|.|::.||::|.
Zfish   748 RHMPDH-----------------------ASEGLALYSVSKLLLIISSVICVSLVLLVFLNLMLF 789

  Fly  1154 LKLWRLEERIDVDLNRRARMPSLAAL-------SELPSTNQEWLELLRDQEMAHENELHKWQQVL 1211
            .|||.||....          |||:.       |:||.|..||.:||..|:..||:||.||::::
Zfish   790 YKLWMLEYTAQ----------SLASWQGLRSHESKLPQTQIEWAQLLESQQRYHESELEKWREII 844

  Fly  1212 QTAIELLKKVSIVCEKITNDSHLR 1235
            ::::.||.::.....|:.....||
Zfish   845 KSSVLLLDEMRESLMKLQKGIGLR 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GramD1B	NP_995623.2	PH-GRAM_GRAMDC	358..451	CDD:275406	54/92 (59%)
		DUF4782	751..897	CDD:292635	49/145 (34%)
gramd1ba	XP_021335128.1	PH-GRAM_GRAMDC	253..346	CDD:275406	54/92 (59%)
		DUF4782	521..669	CDD:318273	50/147 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589818
Domainoid	1	1.000	156	1.000	Domainoid score	I4141
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	441	1.000	Inparanoid score	I1628
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D322809at33208
OrthoFinder	1	1.000	-	-		FOG0000885
OrthoInspector	1	1.000	-	-		otm24894
orthoMCL	1	0.900	-	-		OOG6_101929
Panther	1	1.100	-	-	O	PTHR23319
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X567
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.900