DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GramD1B and gramd2aa

DIOPT Version :9

Sequence 1:	NP_995623.2	Gene:	GramD1B / 33552	FlyBaseID:	FBgn0085423	Length:	1249	Species:	Drosophila melanogaster
Sequence 2:	XP_005166658.1	Gene:	gramd2aa / 555179	ZFINID:	ZDB-GENE-040724-9	Length:	354	Species:	Danio rerio

Alignment Length:	310	Identity:	90/310 - (29%)
Similarity:	144/310 - (46%)	Gaps:	52/310 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 AAPGDSPSS-------RKSSTSSKGKASQAKLSTSSSGRDE-QDISQHRLSDLTQHELSLLRVDR 304
            ||..::||:       |....||:...::.:..:.|..:|: :|:..     ||.|:.|....|.
Zfish     7 AASSEAPSAEGPELQRRPHGYSSRTCRTRVRPKSMSDHQDQAEDVGL-----LTPHDQSEPSKDD 66

  Fly   305 EQ--QVTSSSSTSNEKPAKTSRLSERAKKKSWYNVIYPNYKSRAEDFKKLFKDVPNDERLIVDYS 367
            :.  ::......|.|...|..|.|..:|    ||..|          .|||:.||.:|.|:..||
Zfish    67 DMHFRIHLIDDLSYEDVKKCYRGSTVSK----YNAQY----------HKLFQSVPKEELLMKVYS 117

  Fly   368 CALQRDILVQGRLYVSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISS-GKDK 431
            |||.||||:|||||:|:|::||:||:|..:..|:|....|..:.|.|||.::||.::|:: ...|
Zfish   118 CALLRDILLQGRLYISRNWLCFYANLFGKDIKVAIPVASVRLVKKHKTAGLVPNGLAITTDSSQK 182

  Fly   432 YFFATFTSRDKSFLMLFRVWQNTLMN--KQFSPQEIWQHVHTCYGDELGLTTDDEDYIDPTLNKT 494
            |.|.:..|||..:.:|.|:..:..:|  |..|.::..:..::...||.           |.....
Zfish   183 YVFVSLLSRDSVYDVLRRICTHLQVNGKKILSLKQYMEEPNSLSLDEF-----------PVPEVF 236

  Fly   495 NEPDFDFQTAIDDDSYSQRQSQQSNQSNQSNPLLPQSGNSSASSGGGVRA 544
            ..|| :|...:   .:.::.|..|..|:     ||....:||||...|.|
Zfish   237 PVPD-EFPPVL---KWRRKPSVVSVASS-----LPDLLGNSASSLSAVDA 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GramD1B	NP_995623.2	PH-GRAM_GRAMDC	358..451	CDD:275406	41/93 (44%)
GramD1B	NP_995623.2	DUF4782	751..897	CDD:292635
gramd2aa	XP_005166658.1	PH-GRAM_GRAMDC	108..202	CDD:275406	41/93 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944155at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850