Protein Alignment GramD1B and Gramd1c

DIOPT Version :9

• Sequence 1: NP_995623.2
• Gene: GramD1B / 33552
• FlyBaseID: FBgn0085423
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: XP_038944410.1
• Gene: Gramd1c / 360717
• RGDID: 1305433
• Length: 684
• Species: Rattus norvegicus
• Alignment Length: 1035
• Identity: 234/1035 - (22%)
• Similarity: 389/1035 - (37%)
• Gaps: 387/1035 - (37%)

  Fly   216 ATLGAAPSINIVSSESTRDQTQQPQSVDPNGVAAPGDSPSSRKSSTSSKGKASQAKLSTSSSGRD 280
            |.|..:||....|:..|..|.|             .|||.. ....||.....|.:|..:||...
  Rat     5 AVLWRSPSREEPSTPQTNSQCQ-------------ADSPIV-NDGDSSLATELQGELEENSSPAV 55

  Fly   281 EQDISQHRLSDLTQHELSLLRVDREQQVTSSSSTSNEKPAKTSRLSERAKKKSW-YNVIYPNYKS 344
            ::.|                 |..::|..|:.:.|.:                | :.:....||.
  Rat    56 DESI-----------------VSAKKQGPSTHNWSGD----------------WSFWISSSTYKD 87

  Fly   345 RAEDFKKLFKDVPNDERLIVDYSCALQRDILVQGRLYVSQNYVCFHANIFSWETHVSIKWKDVTA 409
            |.|::::.|..:|:.|:||.||:||||||||:|||||:|:|::||::|||.|||.:||..|::|.
  Rat    88 RNEEYRQQFTHLPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITF 152

  Fly   410 ITKEKTALVIPNAISISSGKDKYFFATFTSRDKSFLMLFRVWQNTLMNKQFSPQEIWQHVHTCYG 474
            :||||||.:|||||.|.:..:|:||.:|.:||:|:|.:||:|||.|::|..:.||.||.:...||
  Rat   153 MTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYG 217

  Fly   475 DELGLTTDDEDYIDPTLNKTNEPDFDFQTAIDDDSYSQRQSQQSNQSNQSNPLLPQSGNSSASSG 539
            .||||..::.:::..::.:..:|....::::||
  Rat   218 TELGLNAEEMEHLSLSIEENVQPRSPGRSSVDD-------------------------------- 250

  Fly   540 GGVRASAPRKSKTKYFFNSSKSSANASASGSDNNKTRESSRKLNKKMKQNAKELTLSSVKPTELS 604
                                        ||..:.|                            .|
  Rat   251 ----------------------------SGERDEK----------------------------FS 259

  Fly   605 VSVTMSAPNVSSSSTAGSTTASSSTIANHTGSGSGSGSLSGSNTAAASGSGSDKMSAEKKVSTAS 669
            .:::::..:||.:|.                    :.||.|:  :...|.|.:...:|:.|
  Rat   260 KAISLTHESVSRASE--------------------TESLDGN--SPERGLGKEGSQSERHV---- 298

  Fly   670 NSAAVAAAEAAQSLASASSGSGSLESKMEMKRKLGKM-HRQREEGKNAAESVPTDVSDSSDS-EE 732
                    ..:.||||              ::|||:: .:..:..||  |.:..|.|.:||| :|
  Rat   299 --------RKSPSLAS--------------EKKLGRVPSKTLDLNKN--EYLSLDKSSTSDSVDE 339

  Fly   733 NNLPFVPTTECTSTHEGRQIVHTILPINVDTLFNLLFSKSKFITDFHAMRKSTDLVLGEWTKNEE 797
            .|:|       ....:||..::.:..|:.:.:|.|||:.|.|:..|...|...|:|...||....
  Rat   340 ENIP-------EKDLQGRLYINRVFHISAERMFELLFTSSHFMQRFTNSRNIIDVVSTPWTVESG 397

  Fly   798 GLQVRTVNVTVQLAASVGPKTSKVTEYQTQRECSKPGELYSIDVNSVNAGIPYAESFSVLIHFCL 862
            |.|:||:..|:.|:..:..|.:..||.||..:.|:..:.|.:|...:...:||.:.|..|..:|:
  Rat   398 GDQLRTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCI 462

  Fly   863 ARTVDDHTMLSIHTQIKYKKSIWGVVKGFIEKNTWAGLEDFFGAQLHA--LQSETCI-PPAKGKG 924
            .|:......|.:.|.:||:|..||::|..||||:|:.||::| .||.:  |..|:.: .|.:..|
  Rat   463 VRSAKQRCRLRVSTDLKYRKQPWGLIKSLIEKNSWSSLENYF-KQLESDLLMEESVLSQPMEDAG 526

  Fly   925 -----RRPRRGMNQQSATSTSTTSITTGALHTATSTDNDSIQESRHPHQQDQHQHQHLHMHHHHH 984
                 ||.||.:|:                 ||...
  Rat   527 KLSSLRRRRRTLNR-----------------TAEPV----------------------------- 545

  Fly   985 HHHGSQHHHHDARHSHHHHHQPLLPHHQQQHPHHWHHRKALLQSGRGTATQIRPLEEAVGPAPAV 1049
                                 |.||  .|:.|               |.......::..|...||
  Rat   546 ---------------------PKLP--SQRSP---------------TDLGFEAKDDITGKRKAV 572

  Fly  1050 DPLETQMLAAGGIPGAAVGAAAGHPLLLEGGKQQQLHHQQQMHHHHLQPHKQHLQQQQLHLGGGD 1114
            |..:|.::
  Rat   573 DSCDTALI--------------------------------------------------------- 580

  Fly  1115 GQPLASGQGSQGHRLRHKGLWLLVILLLCLMLALNVILLLKLWRLEERIDVDLNRRARMPSLAAL 1179
                                 :::.:.|.|::.|||.|.|||.::|.             :..:.
  Rat   581 ---------------------VVMSVFLLLLVLLNVTLFLKLSKIEH-------------ATQSF 611

  Fly  1180 SELPSTNQEWLELLRDQEMAHEN------ELHKWQQVLQTAIELLK--KVSIVCEKITND 1231
            .:|....::.|.|:.|:....||      :.|:.:.|||.:|.:|:  |.|::..:.|.|
  Rat   612 YQLHLQGEKSLNLVSDRLSRTENIQKNKDQAHRLKGVLQDSIVMLEQLKSSLIMLQKTFD 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GramD1B	NP_995623.2	PH-GRAM_GRAMDC	358..451	CDD:275406	54/92 (59%)
		DUF4782	751..897	CDD:292635	45/145 (31%)
Gramd1c	XP_038944410.1	PH-GRAM_GRAMDC	101..194	CDD:275406	54/92 (59%)
		DUF4782	351..498	CDD:406424	45/146 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348360
Domainoid	1	1.000	112	1.000	Domainoid score	I6045
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D322809at33208
OrthoFinder	1	1.000	-	-		FOG0000885
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X567
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850