DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GramD1B and Gramd2a

DIOPT Version :9

Sequence 1:	NP_995623.2	Gene:	GramD1B / 33552	FlyBaseID:	FBgn0085423	Length:	1249	Species:	Drosophila melanogaster
Sequence 2:	XP_006243259.1	Gene:	Gramd2a / 300761	RGDID:	1564007	Length:	377	Species:	Rattus norvegicus

Alignment Length:	221	Identity:	67/221 - (30%)
Similarity:	104/221 - (47%)	Gaps:	26/221 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 GKASQAKLSTSSSGRDEQDISQHRLSDL-TQHELSLLRVDREQQVTSSSSTSNEKPAKTSR---- 324
            ||......:.:|..|...  |.|..:.| |.:.||..::..:.....:..:..|||.|...
  Rat    41 GKMQPIDETVNSYSRSAP--SLHNWTSLATHYGLSNQQMHGKMVPLKNHVSCMEKPGKVQEPPDS 103

  Fly   325 --------LSERAKKKSWYNVIYPNYKSRAEDFKKLFKDVPNDERLIVDYSCALQRDILVQGRLY 381
                    ..|..||......:...|.   :.:.|||||:|.:|.::...|||||||:|:.||||
  Rat   104 SLHWSEGSKGEEIKKYGREGTLLNKYN---QQYHKLFKDIPLEEMVVKVCSCALQRDLLLHGRLY 165

  Fly   382 VSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSG-KDKYFFATFTSRDKSFL 445
            :|.|::||||::|..:..|.|....|..|.|.|.|.::||.::|::. ..||.|.:..|||..:.
  Rat   166 ISPNWLCFHASLFGKDIKVVIPVASVQLIKKHKMARLLPNGLAITTNTSQKYVFVSLLSRDSVYD 230

  Fly   446 MLFRVW-------QNTLMNKQFSPQE 464
            ||.||.       :.:|..::|..:|
  Rat   231 MLRRVCTHLQPSSKKSLSIRKFPEEE 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GramD1B	NP_995623.2	PH-GRAM_GRAMDC	358..451	CDD:275406	39/93 (42%)
GramD1B	NP_995623.2	DUF4782	751..897	CDD:292635
Gramd2a	XP_006243259.1	PH-GRAM_GRAMDC	143..236	CDD:275406	39/92 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348361
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944155at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750